Axle Informatics

Engineer

• Evaluate existing bioinformatics pipelines for performance, accuracy, and maintainability, identifying opportunities for optimization and enhancement
• Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types
• Architect scalable solutions capable of processing thousands of samples efficiently on Google Cloud Platform
• Optimize data input/output operations across pipeline modules to minimize bottlenecks and reduce computational costs
• Prepare and structure analysis outputs for visualization platforms and downstream statistical or machine learning applications
• Implement best practices for workflow versioning, containerization, testing, and documentation
• Collaborate with computational biologists, data scientists, and software engineers to integrate pipelines into broader analytical ecosystems
• Stay current with advances in sequencing technologies and analytical methods, evaluating and incorporating new tools as appropriate

Bioinformatics Engineer