Senior Director, Global Clinical Program Lead

AstraZeneca

Senior Director, Global Clinical Program Lead directing global clinical studies in cardiovascular, renal and metabolic diseases for AstraZeneca. Ensuring ethical standards and compliance in clinical research.

Posted 7/15/2026full-timeBoston • Maryland, Massachusetts • 🇺🇸 United StatesSenior💰 $288,059 - $432,089 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in clinical research, including study design, protocol development, and regulatory compliance, with a strong focus on patient safety and ethical considerations. Possesses advanced knowledge in Cardiovascular, Renal, Metabolic, and Liver Disease, along with effective communication and leadership skills to collaborate with diverse teams and stakeholders.

Highest-signal resume keywords

Clinical Research ExpertiseStudy Design and Protocol DevelopmentBiostatistics KnowledgeRegulatory ComplianceLeadership and Collaboration Skills

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Trial MonitoringData InterpretationPharmacovigilanceStatistical AnalysisClinical Study Report Preparation

Soft Skills

TeamworkEffective CommunicationPresentation SkillsTrust and OpennessCultural Sensitivity

Certifications & Qualifications

M.B.B.S.M.D.PhDPharmD

Industry Keywords

Cardiovascular DiseaseRenal DiseaseMetabolic DiseaseLiver DiseaseGood Clinical Practice (GCP)

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Provides strategic medical and scientific knowledge (Cardiovascular, Renal, Metabolic, and/or Liver Disease) and supports the design, initiation, execution, completion, and interpretation of a clinical study
Is accountable for study designs
Is accountable to deliver medical information, answers, and clarifications to Regulators, Ethic Committees, Marketing Companies, Investigators/Sites
Often works as a Global Clinical Head (GCH) delegate across several studies (e.g. a paediatric programme, or a set of mechanistic/differentiating studies)
Can be the clinical representative on indication Global Product Teams and/or other sub-teams
Has the knowledge to work across projects, with a fast learning curve when moving into new disease area
Is accountable to the Global Clinical Head (GCH) or delegate for the medical aspects and designs of studies
Is responsible for driving decisions within Study Team (ST) remits together with other ST members and for solving medical issues in the study team
Is accountable for the medical and ethical components of studies including patient safety on a study level in compliance with GCP
Is accountable for delivery of the clinical components of all relevant study documents (e.g Protocol, Amendments, Statistical Analysis Plan, Informed Consent Form, Case Report Forms, and Safety and Risk-Based Monitoring Plans)
Is accountable for ensuring that safety surveillance on a study level including the process for Adverse Events (AE)/ Serious AE reporting, the querying of missing/unclear data, the review of blinded safety data, and the escalation to the GCH/Global Safety Physician when needed.
Is medically accountable for international investigator meetings, and supports Marketing Companies (MC) in national activities
Approves (with the GCH) the Clinical Study Report; including preparation and production thereof (Introduction, Results, Discussion).
Is accountable for ST induction and education of new members in the study team, as well as others involved in the study
Collaborates seamlessly and efficiently with global colleagues at other R&D sites
May be accountable to GCH (or delegate) and leadership for identifying risks and proposing mitigation strategies to deliver successful Phase II, III, IV or Life Cycle Management studies
Stays updated on relevant scientific literature
Delivers analyses of clinical data in a balanced, statistically sound fashion, to drive interpretations and further idea generation
Serves as a source of medical expertise for the Product Team, in analyses and interpretation of medical data
Maintains a high degree of understanding and awareness on new and emerging medical development, globally.
Works with international colleagues and with external Alliance partners on development initiatives and regulatory issues
Applies strategic intent of AstraZeneca when working with Alliance partners, Regulatory Authorities, payers, opinion leaders, prescribers and consumers of AstraZeneca products
Able to provide guidance for investigator-initiated trials in cooperation with regional marketing companies
Accountable for building trustworthy relationships with steering committees/executive committees with AROs/CROs
Maintains strong networks globally with KEEs, prescribers, regulators and payers

Requirements

What you’ll need

Graduate of a recognized school of medicine with an M.B.B.S., M.D. degree or equivalent, and/or a graduate of a scientific doctorate (e.g. PhD or PharmD) or equivalent in a scientific discipline or Pharmaceutical Medicine
3+ years clinical research expertise in relevant therapy area in study design, protocol development, monitoring and implementing clinical trials, interpreting and reporting trial results
Good knowledge of biostatistics, global regulatory environment and pharmacovigilance
Proven teamwork and collaboration skills
Fluent in oral and written English
Good presentation skills and effective communication
Leadership qualities, with particular focus on collaborative working skills, trust and openness, irrespective of cultural setting

Benefits

Comp & perks

qualified retirement programs
paid time off (i.e., vacation, holiday, and leaves)
health, dental, and vision coverage