Director – CVRM Genomics Therapeutic Area Lead

AstraZeneca

Director leading CVRM Genomics strategy at AstraZeneca. Supporting population genomics to improve disease understanding and therapeutic development.

Posted 6/9/2026full-timeBoston • Massachusetts • 🇺🇸 United StatesSenior💰 $181,570 - $272,356 per yearWebsite

About the role

Key responsibilities & impact

Support the CVRM Genomic strategy for CGR, ensuring strong alignment to unmet patient needs.
Bring clinical reasoning and genetic insight together to identify disease mechanisms.
Integrate genomic, multi-omic, clinical, biomarker, and real-world evidence data to evaluate disease heterogeneity.
Collaborate with CVRM TA leadership to apply population genomic insight to inform patient selection.
Contribute to scientific collaboration across AstraZeneca and the global research community.
Inspire cross-functional teams of scientists, clinicians, geneticists, and data scientists toward shared goals.

Requirements

What you’ll need

MD (or international equivalent) and/or relevant PhD with deep understanding of CVRM disease biology.
5+ years experience in clinical research and/or drug development in pharmaceutical or academic environments
Demonstrated ability to apply human genetics or multi-omics to inform disease mechanisms.
Experience in genetic epidemiology and/or rare variant interpretation.
Proven track record working in complex, cross-functional scientific or clinical research.
Collaborative, patient-centered approach working across disciplines.
Experience contributing to clinical trial design, patient enrichment strategies, or biomarker-driven study planning.
Excellent communicator able to convey clinical reasoning and genomic insights.

Benefits

Comp & perks

Health, dental, and vision coverage in accordance with the terms of the applicable plans.
Qualified retirement programs
Paid time off (i.e., vacation, holiday, and leaves)

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

clinical researchdrug developmenthuman geneticsmulti-omicsgenetic epidemiologyrare variant interpretationclinical trial designpatient enrichment strategiesbiomarker-driven study planning

Soft Skills

collaborative approachpatient-centered approachexcellent communicationcross-functional teamworkscientific collaboration

Certifications

MDPhD