Executive Director, Global Projects Leader – Strategic Regimens
AstraZeneca
full-time
Posted on:
Location Type: Office
Location: Gaithersburg • Maryland, Massachusetts • 🇺🇸 United States
Visit company websiteSalary
💰 $246,070 - $369,104 per year
Job Level
Senior
About the role
- overall leadership and accountability of multiple, global cross-functional early project teams delivering platform studies with embedded translational medicine research to establish proof-of-concept data enabling Phase III investment strategies
- prioritize and evaluate rational combination regimens across major AZ research platforms and treatment modalities and with the potential for external partnering
- accountable for the strategic leadership and execution for candidate combination regimens
- align prioritization across early- and late-stage research units to advance the solid tumour pipeline
- lead global matrix teams that develop and execute Ph2 platform studies evaluating combination regimens through proof of concept leading to Phase III investment
- responsible for ongoing linkage between early- and late-stage Oncology R&D teams to develop novel regimens with transformational potential
- holds accountability for the strategy, budget, timeline and execution of platform studies and Ph3 supporting data generation
- ensures platform studies support life cycle management strategies and integrated product development plans of AZ’s emerging portfolio
- leads and communicates the project development strategy at governance meetings to gain endorsement and to secure funding
- leads the global project team to effectively communicate and manage risk
- responsible for monitoring emerging data and for adjusting strategy when necessary
- responsible for maintaining a high degree of team effectiveness through collaboration, influence, and, as necessary, coaching and mentoring of cross-functional team members
- maintains relationships with external investigators to ensure projects are consistent with evolving clinical care and experimental approaches
Requirements
- Graduate degree such as a PharmD, PhD, or an MD/PhD
- 10 Industry experience in drug development including experience in early phase clinical drug development and regulatory knowledge
- Strong knowledge and understanding of the Oncology therapeutic area with experience in diverse biological modalities
- Understanding of the evolving clinical landscape in oncology
- Demonstrated experience leading and motivating teams in a highly matrixed environment
- Proven record of cultivating and managing internal and external cross-functional collaborations
- Demonstrated success in influencing colleagues and senior leaders in various departments
- Must demonstrate high integrity
- Experience in development of both small molecules and biologics, including ADCs, RCs, and/or IO (Immune Checkpoint Inhibitors)
- Experience in the development of platform studies
- Experience developing data and justification leading to successful Ph3 investment decisions
- Experience in the treatment of and/or development of agents for the treatment of prostate cancer
- Experience in due diligence (e.g. asset evaluation, assessment of new biomarker and diagnostic tools)
Benefits
- health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans
- qualified retirement program [401(k) plan]
- paid vacation and holidays
- paid leaves
- short-term incentive bonus opportunity
- eligibility to participate in equity-based long-term incentive program
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard skills
drug developmentearly phase clinical drug developmentregulatory knowledgeOncology therapeutic areabiological modalitiessmall moleculesbiologicsADCsRCsImmune Checkpoint Inhibitors
Soft skills
leadershipteam motivationcollaborationinfluencecoachingmentoringcommunicationrisk managementstrategic thinkingintegrity
Certifications
PharmDPhDMD/PhD