Asklepios BioPharmaceutical, Inc. (AskBio)

Accounting Manager

• Oversee monthly, quarterly, and annual close processes, ensuring timely and accurate financial reporting
• Maintain compliance with internal policies, US GAAP / IFRS, and statutory requirements in all reporting activities
• Prepare and review journal entries, account reconciliations, variance analysis and support preparation of financial statements for internal and external stakeholders
• Manage the consolidation of multiple legal entities, including foreign subsidiaries; ensuring proper translation, elimination, and consolidation entries are recorded accurately
• Support income tax compliance process in partnership with external tax advisors
• Maintain and enhance internal controls over financial reporting, including documentation and testing of accounting policies, procedures, and control activities
• Partner with external auditors to support audit requirements and remediation efforts
• Manage assigned general ledger activities, including accruals, prepaids, intercompany, and complex transactions
• Prepare supporting schedules and analysis for complex areas such as capitalization, compensation, or provisions and provide clear, concise summaries to management when presenting findings
• Assist with balance sheet reviews and provide clear explanations for fluctuations
• Provide guidance on technical accounting matters and research complex issues
• Identify opportunities to streamline accounting processes and enhance efficiency through automation, standardization, and documentation updates
• Support ERP system implementations, upgrades, and optimization initiatives
• Research accounting issues and support the application of relevant standards
• Assist with various other projects/ department tasks as needed during the growth and evolution of the Company

Associate Director, Accounting

Director

• Responsible for development and delivery of the Medical Affairs plan and strategies for AskBio's Neuromuscular programs
• Serve as co-leader of the IPT branding sub-team
• Partner with various departments to develop and implement global Medical Affairs strategies
• Collaborate with clinical study teams to enable recruitment and retention of clinical studies
• Execute and support Medical Affairs activities including key opinion leader engagement, congress planning, and publication planning
• Establish relationships and facilitate interactions with thought leaders and advocacy partners
• Develop KOL engagement plan in collaboration with clinical operations and clinical development
• Develop congress strategy
• Develop publication plans and provide oversight of all publications
• Lead the development and execution of medical educational initiatives
• Lead the medical review process for the Neuromuscular therapeutic area

Senior Director, Medical Affairs, Neuromuscular

• Develop and implement an external engagement strategy for our PD and MSA programs aligned to internal business needs and external community needs
• Manage patient advocacy and external engagement to support AskBio’s development and commercial strategies in Parkinson’s Disease (PD) and Multiple System Atrophy (MSA)
• Identify, develop, and cultivate trust-based relationships with patient advocacy and key patient/caregiver organizations consistent with the phase of development of AskBio clinical programs in CNS
• Be responsible for the development and execution of the PD/MSA medical affairs patient advocacy/external engagement plan and ensure its alignment with overall PD/MSA program goals and key deliverables
• Participate in and support patient organization events, workshops, and conferences to elevate gene therapy awareness and champion patient community engagement, as directed
• Participate as an active member of cross-functional study teams that are responsible for ensuring on-time recruitment and retention of participants for clinical studies
• Create and oversee quarterly community newsletter (AAVengers) for the community
• Communicate progress, metrics and milestone status for PD/MSA to leadership, R&D partners and others
• Engage with patient advocacy groups, foundations, and individual patients to understand their point of view and needs as it relates to patient-focused drug development
• Establish and maintain strong relationships with key collaborators in the patient community
• Collaborate with cross-functional teams to ensure patient perspective is internally understood and incorporated into company culture and patient needs are considered at all stages of product development
• Collaborate with Corporate communications and external agencies to develop patient/advocate awareness of AskBio science and clinical programs
• Manage standing patient council meetings and recruit and organize Patient advisory boards, focus groups, meetings as needed, in support of clinical programs
• Perform other activities as assigned by the VP Medical Affairs and senior management
• Work to cultivate a culture of appreciation for Patients as Partners within Askbio
• Collaborate with Integrated Product Team, Clinical Development, Medical Affairs, Regulatory, Corporate Communications, Human Resources, Legal, Compliance and Partner companies to ensure that core values and corporate brand are represented in internal and external initiatives

Associate Director, Patient Engagement

Vice President

• Lead the global strategic clinical development initiatives for AskBio’s GDNF IPT, fostering cross-functional alignment via open and collaborative discussions
• Lead, manage, and mentor a team of clinical development physicians
• Contribute to budget planning and budget management related to clinical development activities aligned with the IPT goals
• Provide clinical development input and maintain alignment with the CNS Drug Delivery IPT and GDNF IPT development plans
• Contribute to the development and execution of the clinical strategy across GDNF and other CNS programs
• Proactively work to identify clinical risks and implement risk mitigation strategies for complex gene therapy studies
• Partner with cross-functional colleagues (including Clinical Operations, Medical Affairs, Pharmacovigilance, Regulatory, Commercial, Nonclinical, Drug Delivery and CMC) to design, execute and report clinical trials
• Manage the creation and maintenance of critical study documents assigned to Clinical Development (e.g., Clinical Study Protocols (CSPs), Investigator’s Brochures (IB), Informed Consent Forms (ICF), Risk-Based Medical Monitoring Plan, Clinical Study Reports (CSRs), and other key regulatory documents) with high quality and consistency with CDP, TPP and AskBio SOPs
• Partner with Pharmacovigilance and Safety colleagues to provide continuous evaluation of drug safety profile, including safety monitoring of clinical studies and signal detection from post-marketing surveillance.

Associate Director, Accounting

Senior Director, Medical Affairs, Neuromuscular

Associate Director, Patient Engagement

VP, GDNF Clinical Development