argenx

Medical Affairs Operations Manager, Business Project and Operations, BPO

argenx

full-time

Posted on:

Origin:  • 🇺🇸 United States

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Job Level

Mid-LevelSenior

Tech Stack

PMP

About the role

  • Lead organizational transformation and cross-functional strategic projects for US Medical Affairs & Evidence Generation (USMAEG).
  • Lead the annual operating plan (AOP) and ongoing re-forecast cycles for the USMAEG portfolio, including launch scenario modeling and alignment with leadership and Finance.
  • Establish molecule- and indication-level budget trackers; monitor burn rates, identify variances, and drive mitigation actions with Finance.
  • Own monthly/quarterly forecasting and prepare accruals in conjunction with Finance partners.
  • Manage end-to-end procure-to-pay (P2P) for USMAEG: vendor onboarding, requisitions, PO creation/amendment, and invoice processing to policy and cycle-time targets.
  • Develop, negotiate, and execute Statements of Work (SOWs) and change orders with vendors; define scope, deliverables, acceptance criteria, and milestone-based payment schedules with Legal and Procurement.
  • Build dashboards and reports (e.g., Excel, Power BI) providing real-time visibility into budget consumption, forecast accuracy, and vendor performance.
  • Design and execute cross-functional programs; develop integrated plans, timelines, budgets, and KPIs.
  • Lead change management to drive adoption of new processes and systems; facilitate decision-making routines and executive updates.
  • Identify and implement process improvements and automation to streamline operations and increase data quality and scalability.
  • Coordinate stakeholder and vendor engagement to ensure alignment on objectives, deliverables, risks, and interdependencies.
  • Partner with all functions and teams (HQ & Field) across USMAEG as well as Finance, Legal, MAEG and Procurement partners to align plans and enable execution.
  • Facilitate budget-to-milestone linkage with medical value narratives for leadership and governance reviews.

Requirements

  • Bachelor’s degree in Finance, Accounting, Business, Science, or related field; advanced degree or certifications (CPA, MBA, PMP) preferred.
  • 3+ years of biopharma experience in medical affairs, strategic operations, or business/financial operations.
  • Strong financial acumen with experience managing multi-million-dollar operating and project budgets and improving forecast accuracy.
  • Advanced Excel skills and comfort with data visualization (Power BI or similar).
  • Proven strategic project management and planning capability, including KPI design and benefits realization.
  • Contracting and vendor management expertise, including SOW structuring, milestone-based payments, and change control.
  • Excellent communication, collaboration, and stakeholder/vendor management; ability to influence across levels.
  • Detail-oriented with strong organizational skills and proficiency with digital tools/AI to enhance decision-making.
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