Vice President – Inflammatory and Immune Disease Biomarker Development
Apogee Therapeutics
full-time
Posted on:
Location Type: Remote
Location: United States
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Salary
💰 $320,000 - $355,000 per year
Job Level
About the role
- Lead the strategic planning and execution of biomarker discovery and development programs for inflammatory and immunology diseases, focusing on atopic dermatitis, asthma, COPD and EOE and particularly late-stage clinical development
- Develop and articulate the late-stage clinical and post-launch strategic vision for the biomarker programs to internal and external stakeholders
- Collaborate with internal and external stakeholders to integrate our biomarker discovery and development efforts into our development programs, including clinical trials and BLAs
- Oversee the Biomarker Discovery and Development team to drive efforts through a combination of in vitro/in vivo and in silico data analyses, in house and in collaboration with external partners
- Together with the Senior Director-Biomarker Discovery and Development develop and implement biomarker strategies to demonstrate the clinical utility of novel biomarkers and the distinction of patient populations and responders as well as additional indications
- Stay current on emerging trends and technologies in biomarker discovery and development, and implement best practices to ensure the success of our programs
- Provide strategic input and leadership to cross-functional program and functional teams to drive the development of novel, innovative therapies for inflammatory and immunology diseases
Requirements
- PhD or MD in a relevant scientific discipline with at least 15 years of track-record in senior leadership roles in biomarker discovery and development, preferably in the field of inflammatory and immunology diseases
- Proven success in leading biomarker discovery programs from ideation to clinical validation and a focused understanding on late-stage clinical development including Phase 3 trials with biologics and BLAs is required. Experience in I&I, atopic dermatitis, asthma, COPD and/or EOE a plus
- Excellent communication skills and ability to articulate and communicate complex strategic vision with a variety of internal and external stakeholders
- Deep hands-on knowledge of the antibody development process and regulatory requirements for biomarkers in clinical trials and for BLA-submissions. Strong preference for candidates with late stage clinical and post launch experience
- Expertise in collaborating with external partners and key opinion leaders in the field of inflammatory and immunology diseases
- Strong leadership and communication skills fully aligned with our C.O.R.E. values, with the ability to effectively lead your internal team and fully integrate this team from early- to late-stage clinical development efforts
- Position requires up to 30% travel including mandatory in-person attendance at All Hands meetings typically held twice per year as well as travel to Apogee offices in Boston and San Francisco.
Benefits
- A great culture, grounded in our C.O.R.E. values: Caring, Original, Resilient and Egoless
- Opportunity to work in a fast-paced, highly dynamic environment where you help shape the culture and company, wear multiple hats, and learn quickly
- Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits
- We provide competitive time off, including three weeks PTO, two one-week company-wide shutdowns a year and dedicated paid sick leave
- Commitment to growing you professionally and providing access to resources to further your development
- Apogee offers regular all team, in-person meetings to build relationships and problem solve
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard skills
biomarker discoveryclinical developmentin vitro data analysisin vivo data analysisin silico data analysisclinical validationantibody development processregulatory requirementsBLA submissionsPhase 3 trials
Soft skills
leadershipcommunicationstrategic visioncollaborationarticulation of complex ideasstakeholder engagementteam integrationcross-functional teamworkproblem-solvingadaptability
Certifications
PhDMD