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PhD Student – Infection Biology, Biomedical Materials
AO FoundationPhD student in infection biology and biomedical materials at AO Research Institute Davos. Engaging in advanced research on bacterial infections and neutrophil interactions.
About the role
Key responsibilities & impact- Establish and optimise advanced 3D in vitro infection models (e.g. staphylococcal abscess communities)
- Investigate early events in infection establishment, including bacterial aggregation, fibrin encapsulation, and antibiotic tolerance
- Characterise neutrophil–bacteria interactions, including phagocytosis, ROS production, and bacterial killing
- Identify and evaluate immunomodulatory compounds that enhance neutrophil function
- Perform cell culture and co-culture experiments using primary human neutrophils and bacterial pathogens
- Apply advanced techniques including confocal microscopy, flow cytometry, and molecular assays
- Analyse and interpret complex experimental datasets
- Contribute to interdisciplinary collaboration with biomaterials researchers within the PREPARE project
Requirements
What you’ll need- Master’s degree in microbiology, infection biology, immunology, or a related life science discipline
- Practical experience in microbiology and/or host–pathogen interaction studies
- Experience with cell culture and immunological assays (e.g. flow cytometry, microscopy)
- Strong interest in infection biology, innate immunity, and translational research
- Ability to design, plan, and execute experimental studies independently
- Excellent communication skills in English
- Motivation to work in a highly interdisciplinary and collaborative environment
- Additional desirable skills:
- Experience working with primary immune cells (especially neutrophils)
- Familiarity with 3D cell culture or infection models
- Knowledge of bacterial physiology, antibiotic tolerance, or biofilms
- Experience with advanced imaging or transcriptomic approaches
- Interest in translational research and biomaterials-based therapeutic strategies
Benefits
Comp & perks- An interesting and varied job in an exciting and innovative organization
- The opportunity to be part of a highly committed international team
- Modern infrastructure
- High degree of flexibility regarding working hours and location (depending on operational requirements)
- Generous package of social benefits, including supplementary vacation days and pension scheme contributions
- Internal skills training opportunities and support for continued education
ATS Keywords
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Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard Skills & Tools
3D In Vitro Infection ModelsBacterial AggregationFibrin EncapsulationPhagocytosisROS ProductionAntibiotic ToleranceFlow CytometryConfocal MicroscopyMolecular AssaysData Analysis
Soft Skills
Excellent Communication SkillsMotivation For CollaborationIndependent Experimental Design