Clinical Development Director – Early Development, Cardiometabolic/General Medicine

Amgen

Clinical Development Director leading early phase clinical development for cardiometabolic/general medicine compounds at Amgen. Collaborating with teams to design and deliver innovative clinical trials.

Posted 7/23/2026full-timeRemote • 🇺🇸 United StatesLead💰 $274,788 - $371,773 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in early phase clinical development, including protocol development, trial design, and data analysis, with a strong foundation in cardiometabolic and general medicine. Proven ability to collaborate effectively across multidisciplinary teams and communicate complex information to diverse stakeholders.

Highest-signal resume keywords

MD Or DO DegreeBoard Certification In Internal Medicine, Cardiology, Or EndocrinologyClinical Trial MethodologyDrug Development ExperienceLeadership Qualities

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Trial DesignData Review And AnalysisProtocol DevelopmentPharmacodynamic Data EvaluationPharmacokinetic Data EvaluationClinical Biomarker StrategyInformed Consent PreparationRegulatory SubmissionsStudy Start UpMonitoring Clinical Trials

Soft Skills

Interpersonal SkillsPresentation SkillsEffective CommunicationTeam CollaborationDecision-Making

Certifications & Qualifications

Board Certification Or Eligibility

Industry Keywords

Cardiometabolic MedicineGeneral MedicineEarly Phase Clinical TrialsClinical ResearchPharmaceutical IndustryMatrix EnvironmentPublication Track Record

About the role

Key responsibilities & impact

Lead the early phase clinical development of compounds from first-in-human studies through proof-of-concept
Collaborate on teams to support the design and delivery of early phase clinical trials
Support protocol development, study start up, data review, monitoring and analysis activities
Contribute to the design and implementation of the early clinical development strategy for cardiometabolic/general medicine therapeutic candidates
Contribute to the preparation of clinical development plans, clinical study protocols, informed consents, Investigator Brochures, and Ethics Committee and regulatory agency submissions
Review and evaluate clinical study safety, efficacy, pharmacodynamic and pharmacokinetic data
Contribute to the strategy and use of clinical biomarkers to facilitate drug development
Actively collaborate with Amgen Precision Medicine, Research, Late Development, Regulatory, Safety and Commercial colleagues
Contribute to the evaluation of external licensing or partnering opportunities within the cardiometabolic/general medicine therapeutic areas
Collaborate with external experts to provide biomedical expertise and strategic guidance to cardiometabolic/general medicine Early Development teams

Requirements

What you’ll need

MD or DO degree from an accredited medical school AND 2 years of industry or academic/basic sciences/clinical research experience
Board certification or eligible (Internal Medicine, Cardiology, or Endocrinology)
Residency training in Internal Medicine and relevant subspecialty
Understanding of cardiometabolic and general medicine pathophysiology
Experience in basic research and/or clinical trial methodology
3+ years of relevant drug development experience in the pharmaceutical industry and/or academia, preferably in early stage clinical trials
Experience collaborating with pharmaceutical sponsors
Experience in designing, monitoring and implementing clinical trials and interpreting trial results
Demonstrated leadership qualities; capable of conducting studies as part of a team
Experience within a matrix environment, contributes to decision-making and reaching alignment in order to meet challenging timelines
Publication track record
Excellent interpersonal and presentation skills; able to communicate effectively with internal stakeholders, as well as external partners and collaborators.

Benefits

Comp & perks

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions
group medical, dental and vision coverage
life and disability insurance
flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible.