Clinical Development Director – Cardiovascular

Amgen

Lead medical and clinical development activities for cardiovascular assets at Amgen. Collaborate with cross-functional teams to drive clinical strategy and execution.

Posted 6/16/2026full-timeRemote • 🇺🇸 United StatesLead💰 $274,788 - $371,773 per yearWebsite

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Lead medical and clinical development activities for assets within the General Medicine therapeutic area
Accountable for clinical strategy, study-level medical leadership, cross-functional decision-making, and support of program execution from early clinical development through late-stage studies
Partner closely with Clinical Operations, Regulatory, Safety, Biostatistics, Medical Affairs, Data Management, and other functional teams
Provide clinical and medical leadership for one or more General Medicine programs or studies
Support the development, execution, and communication of global clinical development strategies for cardiovascular assets across all stages of development
Collaborate with global teams to integrate medical, scientific, regulatory, commercial, and market access perspectives into development programs
Build and maintain strategic scientific relationships with key opinion leaders and external experts
Provide clinical and scientific leadership in the design, conduct, analysis, and interpretation of clinical trials
Contribute to the authoring and review of clinical documents, safety evaluations, and risk-benefit assessments
Participate in regulatory interactions and support submissions to global health authorities
Interpret clinical trial results and contribute to data-driven development decisions
Present scientific and clinical data at various forums as delegated by the Global Development Leader
Identify emerging scientific opportunities and unmet medical needs in cardiovascular medicine to inform future development strategies
Contribute to lifecycle management strategies and provide clinical content for regulatory submissions.

Requirements

What you’ll need

MD or DO degree from an accredited medical school AND 2 years of clinical development experience
5+ years of clinical research experience and/or basic science research combined with clinical teaching and patient care activities in cardiovascular disease
Clinical research experience in the biopharmaceutical industry (biotechnology, pharmaceutical, or CRO environment)
Strong working knowledge of clinical trial design, execution, and interpretation, biostatistics, adaptive trial methodologies, and evidence-generation strategies
Proven ability to work across matrixed teams and influence without direct authority
Strong understanding of cardiovascular clinical endpoints, biomarkers, imaging modalities, and contemporary treatment guidelines
Sound scientific and clinical judgment with the ability to evaluate complex benefit-risk profiles
Working knowledge of Good Clinical Practice (GCP), FDA, EMA/CHMP regulations, ICH guidelines, and global regulatory requirements
Excellent written and verbal communication skills, including the ability to communicate complex scientific concepts to diverse audiences
Demonstrated success functioning as a medical leader within a highly matrixed global organization
Strong strategic thinking, problem-solving, and decision-making capabilities with a track record of delivering results in complex development programs.

Benefits

Comp & perks

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions
Group medical, dental and vision coverage
Life and disability insurance
Flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible.

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

clinical developmentclinical trial designbiostatisticsadaptive trial methodologiesevidence-generation strategiescardiovascular clinical endpointsbiomarkersimaging modalitiesGood Clinical Practice (GCP)regulatory submissions

Soft Skills

influence without direct authorityscientific and clinical judgmentwritten communicationverbal communicationstrategic thinkingproblem-solvingdecision-makingcollaborationleadershiprelationship building

Certifications

MDDO