Principal Engineer – Global Reliability Network Lead

Amgen

Principal Engineer leading Global Reliability Network in Amgen focusing on reliability data and maintenance strategies. Collaborating with engineering teams to optimize asset performance across manufacturing operations.

Posted 6/2/2026full-time🇺🇸 United StatesSeniorWebsite

Tech Stack

Tools & technologies

CloudPMP

About the role

Key responsibilities & impact

Lead the Global Reliability Network
Lead a network of site reliability engineers, maintenance leaders, system owners, and technical SMEs.
Develop and execute the Reliability Network strategy, goals, milestones, and maturity plans.
Share reliability KPIs, bad actor trends, equipment improvements, lessons learned, and reusable solutions.
Represent reliability priorities and recommendations in senior engineering governance forums.
Turn data insights into equipment improvements
Use CMMS data, Asset Performance Monitoring, Plant Pulse, PdM findings, and site input to identify recurring failures, high-risk assets, downtime drivers, and bad actors.
Convert reliability insights into corrective actions, equipment improvements, PM/PdM optimization, spare parts strategies, and capital recommendations.
Track improvement actions, verify benefits, and scale successful practices across sites.
Advance asset criticality and maintenance strategy
Define and maintain a standard risk-based asset criticality approach across sites.
Use criticality to prioritize maintenance strategies, work execution, spare parts, lifecycle planning, and performance monitoring.
Standardize maintenance strategies based on criticality, failure modes, operating context, and performance history.
Support RCM, FMEA/FMECA, PM optimization, predictive maintenance, and condition-based maintenance approaches.
Lead Asset Performance Monitoring and PlantPulse adoption
Define business requirements for asset health, criticality, failure modes, risk ranking, performance monitoring, and continuous improvement.
Partner with SAP EAM, Technology/IS, site engineering teams, the Reliability Network, and SMEs to support deployment, training, adoption, and data quality.
Serve as PlantPulse business owner to ensure tools address reliability pain points, support troubleshooting, and generate actionable equipment insights.
Connect reliability to business value
Partner with OPEX teams to identify reliability improvements that unlock capacity and reduce downtime.
Translate recurring failures and reliability constraints into business impact.
Support lifecycle risk visibility for critical assets, including deterioration, obsolescence, maintenance cost, reliability concerns, and end-of-life planning.
Integrate reliability principles into capital projects from conceptual design through turnover.

Requirements

What you’ll need

Doctorate degree & 2 years of engineering industry experience OR Master’s degree & 4 years of engineering industry experience OR Bachelor’s degree & 6 years of engineering industry experience OR Associate’s degree & 10 years of engineering industry experience OR High school diploma/GED & 12 years of engineering industry experience
Bachelor's degree in Engineering.
Experience in maintenance, reliability, engineering, asset management, manufacturing operations, and/or engineering digital transformation.
Experience leading cross-functional initiatives in site, multi-site, or global environments.
Strong knowledge of CMMS/EAM and asset performance monitoring systems, such as SAP, Maximo, or equivalent.
Working knowledge of asset criticality, RCM, FMEA/FMECA, RCA, PM optimization, PdM, condition-based maintenance, and reliability KPIs.
Ability to translate site needs into scalable business processes, digital product requirements, and improvement actions.
Strong stakeholder management, communication, network leadership, and change leadership skills.
Experience with analytics or dashboarding tools such as Power BI, Spotfire, SAP Analytics Cloud, or equivalent.
Experience in GMP, biopharmaceutical manufacturing, GxP research, laboratory, or other regulated operations.
Familiarity with ISO 55000, ISO 14224, SMRP, Uptime Elements, or similar reliability and asset management frameworks.
Certification such as CMRP, CRL, PMP, Lean Six Sigma, or asset management certification.
Experience deploying predictive maintenance, condition monitoring, smart sensors, AI-enabled analytics, or advanced asset health technologies.
Experience developing business cases for reliability, maintenance, lifecycle asset management, or capacity improvement projects.
Fluent English proficiency, written and verbal.
Availability to commute to the nearest Amgen operation site as business needs arise, including for meetings, training, operational support, or other business-critical activities.

Benefits

Comp & perks

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions
group medical, dental & vision coverage
life & disability insurance
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models where possible.

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Hard Skills & Tools

reliability engineeringasset managementpredictive maintenancecondition-based maintenancefailure modes and effects analysis (FMEA)root cause analysis (RCA)preventive maintenance (PM) optimizationdata analyticsasset criticalityengineering digital transformation

Soft Skills

stakeholder managementcommunicationnetwork leadershipchange leadershipcross-functional leadershipstrategic planningproblem-solvingdata-driven decision makingcollaborationtraining and development

Certifications

CMRPCRLPMPLean Six Sigmaasset management certification