Principal Scientist – Inflammation Biomarkers
Amgen
full-time
Posted on:
Location Type: Remote
Location: United States
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Salary
💰 $164,066 - $196,151 per year
Job Level
About the role
- Help drive scientific and technical plans collaboratively with other members of the Precision Medicine function
- Successfully partner with cross-functional stakeholders to drive clinical biomarker innovation for clinical-stage assets in inflammatory diseases
- Preparing clinical biomarker strategies, leading biomarker development, implementation, and execution for one or more programs
- Responsible for biomarker elements in clinical protocols, biomarker analysis plans, regulatory submissions, investigator meetings, advisory boards and publications
- Build productive relationships with team members and functional groups for integrating an aligned and prioritized clinical biomarker evidence plan that addresses clinical objectives and translational research
- Partner with cross-functional stakeholders including to drive biomarker innovation at product level
- Establish and implement biomarker studies and collaborations with academic laboratories/KOLs
- Interpret and communicate key clinical biomarker findings to cross-functional teams including Precision Medicine teams and leadership
- Responsible for robust clinical biomarker plans to deliver patient stratification/selection, pharmacodynamics, mechanism of action and resistance evidence from clinical trial samples
Requirements
- Doctorate degree in a bioscience or medical discipline and 2 years of industry experience
- Or Master’s degree in a bioscience or medical discipline and 4 years of industry experience
- Or Bachelor’s degree in a bioscience or medical discipline and 6 years of industry experience
- Or Associate’s degree in a bioscience or medical discipline and 10 years of industry experience
- Or High school diploma / GED and 12 years of directly related industry experience
- PhD with 3 or more years pharmaceutical industry experience, developing biomarker strategies in a clinical development setting and/or in preclinical biomarker discovery/validation
- Knowledge and translational biomarker experience in inflammation is highly desirable
- Strong background in immunology, cell biology and genomics
- Clinical development experience working with cross-functional teams conducting clinical trials
- Experience in developing program-based strategies for pharmacodynamic, predictive, and exploratory biomarkers
- Experience implementing a broad array of biomarker platforms and technologies to support clinical-stage programs
- Demonstrated ability to establish and implement biomarker studies and collaborations with academic laboratories/KOLs
- Experience in assay development and qualification and analysis of clinical samples
- Experience managing biomarker assay outsourcing processes with external vendors and CROs
- Poise and professionalism with strong communication and influencing skills in a dynamic environment.
Benefits
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions
- group medical, dental and vision coverage
- life and disability insurance
- flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible.
Applicant Tracking System Keywords
Tip: use these terms in your resume and cover letter to boost ATS matches.
Hard skills
biomarker developmentbiomarker strategiesclinical trial analysisassay developmentpharmacodynamicspredictive biomarkersexploratory biomarkersbiomarker platformsbiomarker validationclinical sample analysis
Soft skills
collaborationcommunicationinfluencingrelationship buildingleadershiporganizational skillsprofessionalismteamworkadaptabilityproblem-solving