Senior Endpoint Systems Engineer – Hybrid

Ambry Genetics

Senior Endpoint Systems Engineer at Tempus managing the health and security of global endpoint fleet. Collaborating with IT teams to architect solutions in a dual-platform environment.

Posted 7/11/2026full-timeChicago • Illinois • 🇺🇸 United StatesSenior💰 $130,000 - $145,000 per yearWebsite

Tech Stack

Tools & technologies

JamfMacOSPythonSwiftVMware

About the role

Key responsibilities & impact

Architect, optimize, and maintain our global Unified Endpoint Management (UEM) infrastructure using Microsoft Intune, Jamf Pro, and VMware Workspace ONE
Design and scale automated deployment, provisioning, and configuration management workflows for Windows 10/11 and macOS hardware
Standardize and evolve modern deployment frameworks utilizing Windows Autopilot, Apple Business Manager (ABM), and Automated Device Enrollment
Develop, test, and maintain robust code repositories (PowerShell for Windows; Bash/Zsh/Python for macOS)
Partner closely with the Security team to engineer and enforce endpoint security baselines
Lead the integration of endpoint platforms with enterprise identity and access management (IAM) systems
Act as the highest tier of technical escalation for complex endpoint, OS, and software issues
Maintain a forward-looking roadmap for endpoint technologies

Requirements

What you’ll need

5–8+ years of dedicated experience in endpoint engineering, systems administration, or infrastructure architecture within an enterprise environment
Comprehensive, expert-level knowledge of both Windows and macOS operating systems
Deep hands-on engineering experience configuring and managing Microsoft Intune, Jamf Pro, and Workspace ONE at scale
Strong proficiency in PowerShell and Bash/Zsh (Python or Swift is a significant plus) for advanced automation, custom scripts, and utilizing MDM APIs
Proven ability to lead projects independently, collaborate across multi-functional engineering teams, and explain complex technical concepts to non-technical stakeholders

Benefits

Comp & perks

incentive compensation
restricted stock units
medical and other benefits depending on the position

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

Endpoint EngineeringSystems AdministrationInfrastructure ArchitectureWindows 10/11MacOSBash/ZshPythonMDM APIsAutomated DeploymentConfiguration Management

Soft Skills

Project LeadershipCollaborationTechnical Communication