Allen Institute

Research Analyst

• Collect in vivo electrophysiological, optogenetics, and/or optical physiological data from mouse cortex using cutting-edge recording systems
• Train mice to perform various foraging behavioral tasks
• Participate in lab maintenance and weekly tasks
• Carry out analyses to assess overall data quality and use this information to update and refine experimental protocols
• Use histological techniques to identify probe recording location

Research Associate I – In Vivo Electrophysiology, Behavior

• Maintain and propagate human cell lines, optimize and perform plasmid DNA transfections and viral transductions
• Execute molecular biology protocols, including molecular cloning, flow cytometry, quantitative PCR, ddPCR, Illumina amplicon sequencing, RNA-seq, single cell RNA-seq
• Assist in troubleshooting technical barriers in the generation of high quality NGS libraries, from library delivery to cell lines through NGS library generation
• Contribute to the development of new protocols as needed
• Present results and summarize progress to help frame internal decision-making
• Comply with SOPs, good laboratory practices, and regulatory requirements
• Adhere to a team schedule and individual time management
• Maintain accurate laboratory documentation using established methods
• Other duties as assigned

Research Associate I

• Support projects aimed to classify cell types within the brain through generation of high-quality patch-clamp electrophysiology and transcriptomic data
• Execute a variety of laboratory tasks and experiments in a high-throughput laboratory
• Follow Standard Operating Procedures (SOPs)
• Recognize process deviations and participate in troubleshooting
• Operate complex laboratory instrumentation
• Comply with regulatory requirements and maintain accurate laboratory documentation
• Work efficiently in a team environment

Research Associate I, Tissue Processing, Electrophysiology

Software Engineer

• Lead, mentor, and manage a team of engineers and scientists, fostering a culture of collaboration, innovation, rigor and continuous improvement
• Collaborate with senior leadership to develop and execute strategic plans for assay development and process engineering
• Lead the design, integration, validation and implementation of novel molecular, microscopy and software components through successful pipeline implementation
• Drive the development and implementation of engineering best practices, processes, and standards across assay development and end-to-end assay pipelines to ensure high-quality, reproducible deliverables
• Oversee the design, development, and delivery of pipeline capabilities (assay workflows, automation, instrumentation/software integration, and supporting tools) for scientists, ensuring alignment with assay performance requirements and scientific use cases
• Conduct technical assessments and guide complex assay pipeline implementations, ensuring scalable throughput, operational reliability, and appropriate security/privacy controls for the lab-to-data workflow
• Ensure data integrity, quality, and governance for assay pipeline outputs (including sample metadata, QC metrics, provenance, and downstream handoffs) to enable reliable large-scale dataset generation
• Partner with Product Management and cross-functional engineering teams to drive innovation and ensure seamless integration of assay workflows, instrumentation/software components, and data pipeline capabilities
• Act as a technical advisor to key stakeholders, providing insights and recommendations to support decision-making and strategic planning
• Oversee project timelines, budgets, and resource allocation to ensure successful delivery of assay development programs and supporting end-to-end assay pipeline capabilities
• Identify and mitigate risks, manage project dependencies, and ensure alignment with organization goals and objectives
• Stay current with industry trends, emerging technologies, and best practices in high-throughput assay development, workflow automation, instrumentation/software integration, and scalable lab-to-data pipelines
• Champion the adoption of innovative tools, technologies, and methodologies that improve assay pipeline throughput, robustness, reproducibility, and data quality

Associate Director, Assay Development, Process Engineering – Brain Health

• Help maintain a colony of Huntingtons Disease model mice as part of a small team
• Perform euthanasia and collect tissues from subject mice
• Isolate RNA, DNA and protein from tissues and cells
• Analyze transcript and protein levels using established QRTPCR, western blotting and 96-well plate-based assessments
• Conduct cell culture experiments, including maintaining immortalized mammalian cells in culture

Research Associate I – Brain Health

• Perform protein library screening and binder evaluation experiments to generate high-quality, model-ready datasets
• Execute binder screening protocols, including molecular cloning, CLICK/Phage display, FACS, and NGS library preparation and sequencing
• Assist in troubleshooting technical barriers in the generation of high-quality data, from library cloning to delivery to FACS to NGS library generation
• Review and analyze data, participating in quality control and troubleshooting of processes and results
• Contribute to the development of new protocols as needed
• Present results and summarize progress to help frame internal decision-making
• Comply with SOPs, good laboratory practices, and regulatory requirements
• Adhere to a team schedule and individual time management
• Maintain accurate laboratory documentation using established methods

Research Associate I, Protein Binding Screening

Administrative Assistant

• Provide complex administrative support including but not limited to calendar management, events and meeting coordination and logistics planning, agenda and meeting minute management, action item and/or issue monitoring and tracking for team or project accountability
• Schedule and manage internal and external meetings, as well as team events
• Manage employee and external visitor onboarding processes and activities
• Draft, edit and proofread documents for content, spelling, grammar, and typographical errors
• Support preparation of reports and presentations as needed
• Create and maintain spreadsheets, and administrative standard procedures for the team
• Support travel, purchasing and expense reporting for the team
• Provide ongoing operational and administrative support

Senior Administrative Coordinator

Chief Technology Officer

• Support the development and application of AI/ML methods for analyzing multimodal biological data
• Work with datasets such as multi-omics, imaging, and other complex scientific data
• Implement and evaluate machine learning models, including testing different approaches and analyzing results
• Assist in preparing and processing data for modeling and analysis
• Collaborate with scientists, computational biologists, and software engineers across the Institute
• Participate in research discussions, literature review, and code development using collaborative tools (e.g., Git, code review)
• Communicate progress and findings to relevant teams