Akero Therapeutics

Senior Program Director – Regulatory and Clinical Development

Akero Therapeutics

full-time

Posted on:

Location Type: Remote

Location: United States

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Salary

💰 $181,670 - $317,920 per year

Job Level

About the role

  • Own and execute program and portfolio management strategy across Akero’s development organization
  • Serve as primary cross functional integrator, ensuring alignment between strategy, execution, governance and decision making across programs.
  • Partner with Development Therapeutic Area VPs and senior leaders to advance strategic priorities and ensure clear accountability, ownership, and decision rights.
  • Design, implement, and run Akero’s development governance model in alignment with the parent organization.
  • Establish and maintain decision-making frameworks, escalation pathways, and executive visibility into risks, trade-offs, dependencies, and outcomes.
  • Lead Akero Development governance meetings and ensure consistent alignment with parent company processes and expectations.
  • Collaborate with TechOps (CMC) to develop, gain approval, and execute on the project strategy in alignment with parent company
  • Lead cross-functional alignment across departments, proactively identifying and resolving risks, conflicts, and misalignments.
  • Oversee program timelines, integrated development plans, and delivery of key milestones across the portfolio.
  • Manage trade-offs and dependencies, escalating issues to senior leadership as needed to maintain progress and alignment.
  • Identify gaps in capabilities, training, and processes (e.g., GCP training), and partner with Quality to support compliance activities as needed.
  • Establish scalable systems, templates, tools, and best practices for program and portfolio management.
  • Own portfolio-level risk and issue management, ensuring mitigation strategies are proactively developed and executed.
  • Monitor program performance and intervene as needed to keep programs on track.
  • Partner with Finance and leadership on development budgets, forecasting, and resource allocation across the portfolio.
  • Build, mentor, and develop program management talent.
  • Organize and deploy project management support across functional areas and programs.
  • Foster a high-performing, accountable, and collaborative program management culture.

Requirements

  • Minimum of a bachelor's degree required, advanced degree (master's or PhD preferred), preferably within a scientific discipline or other related fields.
  • 15+ years of proven experience in biotech / pharma portfolio and project management at a strategic and operational level
  • Preferred experience working with Phase III trials for liver indications
  • Demonstrated ability to lead transformation initiatives and drive organizational change.
  • Strong financial acumen and experience with budget ownership and planning.
  • Expertise in governance frameworks and decision-making processes.
  • Track record of building and developing high-performing teams.
  • Excellent communication, stakeholder management, and cross-functional leadership skills.
  • Knowledgeable about lab-engineered analogs highly preferred
Benefits
  • medical, dental and vision coverage
  • life insurance
  • disability insurance
  • 401(k) savings plan
  • flexible spending accounts
  • employee assistance program
  • tuition reimbursement program
  • group legal
  • critical illness
  • identity theft protection
  • pet insurance
  • auto/home insurance
  • sick time policy
  • flexible vacation policy
  • parental leave policy
Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools
program managementportfolio managementgovernance frameworksbudget planningrisk managementproject strategyPhase III trialscompliance activitiesdecision-making processesfinancial acumen
Soft Skills
leadershipstakeholder managementcross-functional collaborationorganizational changementoringcommunicationproblem-solvingaccountabilityteam developmenthigh-performing culture