Valence Laboratories

Research Scientist, Virtual Cell Modelling, Perturbative Biology

Valence Laboratories

full-time

Posted on:

Location Type: Hybrid

Location: MontréalCanada

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Salary

💰 CA$188,200 - CA$237,100 per year

Tech Stack

About the role

  • Research and develop generative and distributional models (e.g., flow matching, diffusion models) to predict high-dimensional cellular responses.
  • Build and maintain ML systems capable of processing massive multiomics datasets on high-performance compute clusters.
  • Work closely with colleagues to ensure model predictions are interpretable, trustworthy, actionable, and grounded in real experimental outcomes.
  • Help design and implement rigorous evaluation metrics that test generalization across for cellular context, unseen perturbations and covariates, going beyond IID performance to reflect real deployment conditions.
  • Publish findings in top-tier venues (e.g., NeurIPS, ICML, Nature, Science, Cell) and contribute to the broader scientific community.

Requirements

  • PhD (or equivalent) with significant academic or industry research experience in machine learning applied to drug discovery, life sciences or other real-world scientific or engineering problems.
  • Strong background in generative modeling and representation learning, with experience applying these to high-dimensional scientific data (e.g., images, count matrices, graphs); experience with biological data is a plus.
  • Scientific knowledge of biology or chemistry, with familiarity with perturbational / interventional experimental paradigms (e.g., chemical or genetic screens, transcriptomics, high-content imaging).
  • Impactful research track record, including developing ML models for complex real-world data, proposing new training or evaluation approaches, or applying generative methods to scientific problems, particularly in biology or life sciences.
  • Strong technical and engineering skills, including the ability to rapidly prototype and scale ML models, manage large codebases, and maintain reproducible research pipelines; Python proficiency required, experience with compiled languages a plus.
  • Cross-functional comfort, with the ability to work effectively across disciplines (e.g with dry and wet-lab scientists) to ensure models address real scientific questions.
  • Leadership and communication skills: including an authorship record in peer-reviewed conferences (e.g., NeurIPS, ICML, ICLR) or journals (e.g., Nature, Science, Cell).
Benefits
  • comprehensive benefits package
  • annual bonus
  • equity compensation
Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools
generative modelingrepresentation learningmachine learninghigh-dimensional data analysisPythonML model developmentevaluation metricsreproducible researchdata processingmultiomics datasets
Soft Skills
leadershipcommunicationcross-functional collaborationinterdisciplinary teamworkproblem-solvingresearch publicationtrustworthinessactionabilityinterpretabilityscientific inquiry
Certifications
PhD