Senior Director, Global HEOR

Ultragenyx

Senior Director leading Global Health Economics and Outcomes Research strategies for Ultragenyx. Collaborating cross-functionally to mitigate risk and achieve success in global programs.

Posted 5/15/2026full-timeRemote • 🇺🇸 United StatesSenior💰 $254,200 - $314,000 per yearWebsite

About the role

Key responsibilities & impact

Identified as an HEOR subject matter expert, able to provide consultation as an internal HEOR subject matter authority to other departments and responsible for developing HEOR strategy and leadership among cross-functional project teams, to mitigate risk and achieve success, across the portfolio of Ultragenyx programs globally
Generate HEOR data to support clinical development and reimbursement, including design, implementation and analysis of HEOR studies
Proactively collaborates and demonstrates cross-functional leadership across the organization to facilitate alignment around key HEOR endpoints, outcomes and deliverables and partners closely with internal stakeholders, including medical, clinical development, commercial, market access, endpoint development strategy and management team to identify and develop appropriate HEOR strategy to support global development and reimbursement plans across US, Canada, EMEA, LATAM and APAC regions
Identify evidence gaps to inform strategic planning and lead development of new evidence strategies to increase understanding of target patient populations of UGX programs and lead development of new evidence generation strategies to achieve market access across global target patient populations of UGX programs
Review and provide health economics and outcomes research input into clinical development program planning, integrated evidence generation plans, regulatory documents with accuracy and scientific integrity
Provide leadership through influencing without authority across project teams, internally and externally, can identify & lead cross functional teams for external collaborative research partnerships from project inception thru publication(s) and presentation(s)
Represent Ultragenyx as Global HEOR subject matter expert at external professional, scientific meetings and forums

Requirements

What you’ll need

BA/BS in the Life Sciences, Public Health, Epidemiology or Health Economics and MA/MS in the Life Sciences, Public Health, Epidemiology, Health Economics or Pharmacy; Prefer advanced degree in the life sciences (PharmD, PhD, MD)
12 + years of relevant experience in biopharmaceutical industry, with health economics and outcomes research, with clinical background/research experience preferred
Excellent interpersonal and organizational skills with the ability to work well in a multidisciplinary team and across the matrix. Key stakeholders include Medical Strategy, Clinical Development, Regional Market Access, Biostatistics, Molecular Diagnostics, Epidemiology, Global and Regional Commercial
Experience in health economics and outcomes research activities including de novo evidence generation, economic modelling, input into clinical trial design & analysis, evidence- based synthesis from literature, and study design, data management and analysis.
Effective communication of HEOR strategy and findings, both written and verbal, is required.
Self-motivated with the ability to work independently, across multiple assets, and to develop credibility with colleagues, influence decisions with excellent interpersonal and organizational skills with the ability to work well in a multidisciplinary team and across the matrix.
Strong technical expertise in HEOR principles, and knowledge of analytical applications, demonstrating a sophisticated understanding of, and the ability to interpret, quantitative methods is required
Experience in strategic planning and project management, with proficiency in working cross-cultural/global teams
Experience in Gene Therapy and in Global HEOR strongly preferred
Experience in Rare Disease preferred
Travel: approximate 10-25%

Benefits

Comp & perks

Generous vacation time and public holidays observed by the company
Volunteer days
Long term incentive and Employee stock purchase plans or equivalent offerings
Employee wellbeing benefits
Fitness reimbursement
Tuition sponsoring
Professional development plans

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

health economicsoutcomes researchevidence generationeconomic modelingclinical trial designdata managementdata analysisquantitative methodsstrategic planningproject management

Soft Skills

interpersonal skillsorganizational skillscommunication skillsleadershipcollaborationinfluencing without authorityself-motivatedability to work independentlycredibility developmentmultidisciplinary teamwork

Certifications

BA/BS in Life SciencesMA/MS in Life SciencesPharmDPhDMD