Principal Biostatistician – Therapeutic Areas, Oncology / Vaccines

Syneos Health

Principal Biostatistician overseeing training and statistical tasks for drug development at Syneos Health. Mentoring and directing biostatisticians to ensure high quality work across projects.

Posted 6/17/2026full-timeRemote • 🇺🇸 United StatesLeadWebsite

About the role

Key responsibilities & impact

Serves as a statistical department resource, mentors biostatisticians on job skills, and oversees or develops training plans or materials for Biostatistics associates.
Conducts training sessions, or otherwise trains new hires and enhance the skills of existing personnel.
Directs the activities of other biostatistics personnel on assigned projects to ensure timely completion of high quality work.
Provides independent review of project work produced by other biostatisticians in the department.
Provides support across all statistical tasks during the lifecycle of the project, from protocol to CSR.
Prepares or oversees the preparation of Statistical Analysis Plans (SAPs), including development of well-presented mock-up displays for tables, listings, and figures. Collaborates with sponsor, if required.
May be responsible as Lead Biostatician for the statistical aspects of the protocol, generation of randomization schedule, and input to the clinical study report.
Creates or reviews programming specifications for analysis datasets, tables, listings, and figures.
Reviews SAS annotated case report forms (CRFs), database design, and other study documentation to ensure protocol criteria are met and all data is captured as required to support a high quality database and the planned analysis.
Implements company objectives, and creates alternative solutions to address business and operational challenges.
As biostatistics representative on project teams, interfaces with other departmental project team representatives.
Preparing in advance for internal meetings, contributing ideas, and demonstrating respect for opinions of others.

Requirements

What you’ll need

Serves as a statistical department resource, mentors biostatisticians on job skills, and oversees or develops training plans or materials for Biostatistics associates.
Conducts training sessions, or otherwise trains new hires and enhance the skills of existing personnel.
Directs the activities of other biostatistics personnel on assigned projects to ensure timely completion of high quality work.
Provides independent review of project work produced by other biostatisticians in the department.
Provides support across all statistical tasks during the lifecycle of the project, from protocol to CSR.
Prepares or oversees the preparation of Statistical Analysis Plans (SAPs), including development of well-presented mock-up displays for tables, listings, and figures. Collaborates with sponsor, if required.
May be responsible as Lead Biostatician for the statistical aspects of the protocol, generation of randomization schedule, and input to the clinical study report.
Creates or reviews programming specifications for analysis datasets, tables, listings, and figures.
Reviews SAS annotated case report forms (CRFs), database design, and other study documentation to ensure protocol criteria are met and all data is captured as required to support a high quality database and the planned analysis.
Implements company objectives, and creates alternative solutions to address business and operational challenges.
As biostatistics representative on project teams, interfaces with other departmental project team representatives.
Preparing in advance for internal meetings, contributing ideas, and demonstrating respect for opinions of others.

Benefits

Comp & perks

We are passionate about developing our people, through career development and progression;
supportive and engaged line management;
technical and therapeutic area training;
peer recognition and total rewards program.
We are committed to building an inclusive culture – where you can authentically be yourself.
Driven to Deliver – which captures the passion of our colleagues to show up each day and shape solutions that have the ability to dramatically impact someone’s life.
We are continuously building the company we all want to work for and our customers want to work with.

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

biostatisticsStatistical Analysis Plans (SAPs)programming specificationsSASdata analysisrandomization scheduleclinical study reportmock-up displaysdatabase designstatistical tasks

Soft Skills

mentoringtrainingproject managementindependent reviewcollaborationproblem-solvingcommunicationteamworkpreparation for meetingsrespect for opinions