Principal Statistical Programmer – ADAM, TLF

Syneos Health

Principal Statistical Programmer developing statistical programs and collaborating with stakeholders at Syneos Health. Ensuring accuracy and integrity of data while mentoring junior programmers.

Posted 5/22/2026full-timeRemote • 🇺🇸 United StatesLeadWebsite

About the role

Key responsibilities & impact

Develop and maintain statistical programming standards and best practices
Provide technical expertise and leadership in the development of statistical programs
Collaborate with statisticians and other stakeholders to understand and address their programming needs
Ensure the accuracy and integrity of data and statistical outputs
Troubleshoot and resolve programming issues and challenges
Mentor and train junior programmers and other team members
Contribute to the continuous improvement of programming processes and tools
Design and implement efficient programming solutions to meet project requirements
Conduct code reviews and provide constructive feedback to ensure high-quality programming deliverables
Stay updated with the latest advancements in statistical programming and incorporate relevant techniques into practice

Requirements

What you’ll need

8+ years of experience in Clinical SAS, Base SAS, Advance SAS
Strong experience in ADAM & TLF programming including ADaM specifications, dataset generation
Good to have experience of ISDB-ISS, pooling study
Must have experience of client handling, leading studies.
Good to have experience of both safety & efficacy data.
Strong communication skills, problem-solving abilities, and ability to work collaboratively in a dynamic environment.
Certifications SAS Certified Advanced Programmer for SAS 9 or equivalent certification preferred

Benefits

Comp & perks

We are passionate about developing our people, through career development and progression
Supportive and engaged line management
Technical and therapeutic area training
Peer recognition and total rewards program
Inclusive culture – where you can authentically be yourself

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

Clinical SASBase SASAdvanced SASADAM programmingTLF programmingADaM specificationsdataset generationISDB-ISSsafety dataefficacy data

Soft Skills

communication skillsproblem-solving abilitiescollaborative workleadershipmentoringtrainingtechnical expertisetroubleshootingconstructive feedbackcontinuous improvement

Certifications

SAS Certified Advanced Programmer for SAS 9