Associate Director – Director of Drug Substance

Structure Networks, Inc.

Associate Director to Director role focusing on small molecule Technical Operations at Structure Therapeutics. Responsible for drug substance development and commercialization readiness in Shanghai.

Posted 6/1/2026full-timeShanghai • 🇨🇳 ChinaSeniorWebsite

About the role

Key responsibilities & impact

Responsible for Structure Therapeutics’ small molecule Technical Operations projects in terms of the development of drug substances
Support late-stage drug substance activities in contract development and manufacturing organizations (CDMOs)
Focus on late stage and commercialization readiness
Manage all interactions with CRO’s or CDMOs to ensure delivery of high-quality results and reports in time to meet regulatory requirements, including GxPs
Accountable for the delivery of proper documents for regulatory filings
Develop robust and scalable synthetic routes suitable for commercialization
Direct CRO teams to perform experiments to define process parameters intended to develop suitable processes for chemical manufacturing and commercialization
Monitor the progress of projects and provide technical solutions to CRO and CDMOs

Requirements

What you’ll need

Ph. D or M.S’s degree in Organic chemistry, preferred in Organic Synthesis
10+ years of working experience in API development in biotech/pharma industry
Being skilled in the application of GLP/cGMP is required
Extensive drug substance process development background and hands-on experience with working knowledge of cGMP manufacturing
Detail-oriented
Ability to critically evaluate analytical data from a broad range of scientific disciplines
Have both broad and in-depth knowledge as well as hands-on experience in modern organic chemistry techniques
Outstanding problem-solving abilities
Demonstrate knowledge of drug substance development, the ability to troubleshoot process development issues
Project management skills are required
Demonstrate a proven track record in working with and managing CROs and CDMOs for new synthesis design and execution in the lab and manufacturing
Ability to operate effectively within an entrepreneurial and science-driven company environment; self-motivated, delivery-oriented, assertive, able to inspire others, driven and hands-on with unquestionable integrity and the highest ethical standards
Excellent team player
Language required: English and Chinese

Benefits

Comp & perks

Annual performance incentive bonus
New hire equity
Ongoing performance-based equity

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

Organic chemistryOrganic synthesisAPI developmentGLPcGMPDrug substance process developmentAnalytical data evaluationModern organic chemistry techniquesProject managementSynthesis design

Soft Skills

Detail-orientedProblem-solvingCritical evaluationTeam playerSelf-motivatedDelivery-orientedAssertiveInspirational leadershipIntegrityEthical standards

Certifications

Ph.D.M.S.