Spyre Therapeutics

Vice President, Commercial Strategy, Market Access

Spyre Therapeutics

full-time

Posted on:

Location Type: Remote

Location: United States

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Salary

💰 $330,000 - $357,000 per year

Job Level

Lead

About the role

  • Develop the global pricing strategy, including scenario planning, pricing corridors and gross-to-net assumptions
  • Map evidence requirements and gaps to support global payer and HTA decision-making
  • Build early payer engagement strategy and plan
  • Assess patient support landscape and build launch strategy, inclusive of hub, call center, copay, nurse, and field reimbursement
  • Develop US channel strategy for Spyre launch brands
  • Determine optimal global launch waves and sequencing to optimize commercial value
  • Regularly monitor global policy and pricing landscape changes and assess impact to Spyre portfolio
  • Partner with competitive intelligence team to monitor competitor pricing and access dynamics and impact to Spyre
  • Partner with CCO and corporate strategy team to refine commercial strategy as Spyre clinical profiles solidify and the competitor landscape shifts
  • Influence Phase 3 clinical trial design to ensure alignment with key commercial considerations including pricing, access and demand
  • Partner with R&D, Regulatory and Corporate Strategy to refresh target product profile (TPPs)
  • Identify and mitigate key commercial risks ahead of Phase 3 investment decisions
  • Conduct market research to assess drivers of physician adoption and patient access
  • Partner with CCO to build an integrated launch plan, including a detailed commercial launch plan inclusive of commercial resourcing and organizational design
  • Identify and partner with external partners who can support commercial launch preparation
  • Lead commercial forecasting and scenario modeling, incorporating market access dynamics, competitive landscape, and adoption assumptions
  • Partner with Finance team to conduct ROI assessments to aid with portfolio prioritization and launch sequencing strategy
  • Generate insights through engagement with payers, KOLs, and advisors
  • Partner with Medical team to execute cross-functional KOL engagement plan
  • Serve as the commercial lead on Spyre Product Teams
  • Ensure alignment between development strategy and commercial success factors
  • Contribute to Board and investor materials
  • Engage with potential strategics and represent commercial voice in discussions
  • Identify and recruit top talent to join commercial organization as the team grows
  • Lead, develop and mentor future direct reports
  • Other duties as assigned

Requirements

  • 12+ years of experience in biotech/pharma across market access, commercial strategy, and/or marketing
  • Demonstrated experience developing biotech/pharma commercial and access strategy for assets in Phase 2 and Phase 3 development
  • Commercial launch and/or in-line experience, in market access and/or marketing
  • Expertise partnering with R&D, Medical and Regulatory to develop value maximizing Phase 3 designs and TPPs
  • Deep understanding of global payer dynamics, pricing strategy, and patient access/services
  • Experience in commercial forecasting and strategic planning
  • Experience building commercial and cross-functionally integrated launch plans
  • Track record of successfully influencing across functions
  • Excellent communication skills with the proven ability to work effectively in a fast-paced environment.
Benefits
  • Opportunity to work in a fast-paced, dynamic environment where you help shape the culture of our young company, contribute broadly to advance meaningful medicines, and learn quickly.
  • Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits.
  • Unlimited PTO
  • Two, one-week company-wide shutdowns each
  • Commitment to provide professional development opportunities.
  • Remote working environment with frequent in-person meetings to address complex problems and build relationships.
Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools
pricing strategyscenario planningcommercial forecastingmarket accessstrategic planningPhase 2 developmentPhase 3 developmentvalue maximizing designspatient accesscommercial launch
Soft Skills
communication skillsleadershipmentoringinfluencingcollaborationstrategic thinkingorganizational designcross-functional teamworkproblem-solvingadaptability