Principal Software Engineer

Satomic Design

Principal Software Engineer building core software for an automated chemistry platform. Collaborating with cross-functional teams to deliver reliable and executable chemical processes.

Posted 4/12/2026full-time🇺🇸 United StatesLeadWebsite

Tech Stack

Tools & technologies

AWSAzureCloudGoogle Cloud PlatformPythonReactVue.js

About the role

Key responsibilities & impact

Building the core software systems that turn customer intent into reliable, executable chemical reality
Ensuring requests through the API map cleanly onto Satomic’s physical synthesis processes
Partnering closely with chemistry, automation, and data colleagues as a technical peer
Making decisions on what to build, in what order, and why
Being the sole engineer in an early production environment and the first responder for platform incidents and outages
Defining and writing the execution architecture for workflow orchestration and state management
Establishing and documenting engineering standards in active use across the platform
Instrumenting the execution pipeline so failures are automatically detected

Requirements

What you’ll need

Experience building systems from the ground up at an early-stage or high-growth company, making decisions with incomplete information
Experience designing and operating long-running or asynchronous systems where failures are expected and recovery is part of the design
Strong judgment in making architectural tradeoffs, including knowing what to defer and being able to defend those decisions clearly
Hands-on experience with cloud infrastructure (AWS, GCP, or Azure) in a production environment, including compute, storage, networking, and managed services, with comfort making cost and reliability tradeoffs
Experience building or owning web interfaces, including familiarity with modern frontend frameworks (React, Vue, or similar) and the ability to make pragmatic frontend architecture decisions
Experience designing or maintaining CI/CD pipelines and deployment workflows, including staging environments, rollback strategies, and release automation
Comfort choosing and modeling data storage solutions— relational, document, time-series, or otherwise— appropriate to the workload
Experience setting up and maintaining logging, metrics, and alerting to understand and respond to system health in production
Security-conscious design for systems handling sensitive or proprietary data, including practical experience with access controls, secrets management, and reducing attack surface
Experience with incident response and on-call ownership, including triage under pressure, structured post-mortems, and building systems that are debuggable by design
Ability to collaborate with non-software domain experts to translate ambiguous business or scientific requirements into well-scoped, sequenced technical plans
Python experience strongly preferred.

Benefits

Comp & perks

Diversity & Inclusion initiatives
Commitment to helping drive change in the industry
Culture built on inclusion, humility, humanity, and ingenuity.

ATS Keywords

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Hard Skills & Tools

API developmentcloud infrastructureAWSGCPAzurefrontend frameworksReactVueCI/CD pipelinesPython

Soft Skills

judgmentdecision makingcollaborationcommunicationproblem solvingincident responsetriagepost-mortemstechnical planningadaptability