VP of Operations, AI Simulation

SandboxAQ

VP of Operations responsible for operational strategies within the AI Simulation division at SandboxAQ. Leading high-impact teams to advance AI-driven science initiatives.

Posted 5/5/2026full-timeRemote • 🇺🇸 United StatesLead💰 $195,200 - $366,000 per yearWebsite

About the role

Key responsibilities & impact

Provide operational support and leadership to BioSim and ChemSim divisions, running day-to-day business operations including identifying synergies in resource allocation and operationalizing scaling systems.
Lead the transition from high-growth experimentation to scaled operations by optimizing talent density and capacity across PhDs, SWEs, and GTM specialists.
Be responsible for hands-on and end-to-end execution, track velocity across complex milestones, and rapidly shift resources (financial and talent) as requirements arise and shift.
Spearhead the Chemical Simulation business unit during its expansion.

Requirements

What you’ll need

Deep experience in operational leadership, including tenure as a COO, Managing Director, or Head of Ops at venture-backed scaled startups; proven track record of scaling companies from Series B through to mature operations or successful exits.
Deep familiarity with AI or heavy-compute environments; ability to translate the needs of Research Scientists and Executives into tactical execution against business requirements.
A "Builder-Operator" mindset with the ability to pivot instantly from deep-dive spreadsheet/Jira analysis to board-level strategic planning.
Proven expertise in conducting root-cause analysis on both operational delivery failures and human dynamics (attrition, team friction) within multidisciplinary teams.

Benefits

Comp & perks

Comprehensive medical, dental, and vision coverage for employees and dependents with generous employer premium contributions
Retirement savings with company matching
Paid parental leave
Inclusive family-building benefits
Flexible paid time off
Company-wide seasonal breaks
Support for flexible work arrangements that enable sustainable performance
Opportunities for continuous learning and growth through on-the-job development, cross-functional collaboration, and access to internal learning and development programs

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

operational leadershiproot-cause analysisscaling operationstalent density optimizationcapacity managementhigh-growth experimentationend-to-end executionmilestone trackingfinancial resource managementhuman dynamics analysis

Soft Skills

leadershipstrategic planningadaptabilityproblem-solvingcommunicationteam managementcollaborationanalytical thinkingdecision-makingpivoting