Associate Director, Quantitative Pharmacology

Regeneron

Associate Director leading model-informed drug development strategies for therapeutic areas at Regeneron. Collaborating cross-functionally to inform regulatory strategy from development through submission.

Posted 5/31/2026full-timeRemote • New York • 🇺🇸 United StatesSenior💰 $176,100 - $287,300 per yearWebsite

About the role

Key responsibilities & impact

Leading model-informed drug development strategies supporting one or more therapeutic areas across modalities including antibodies, siRNA, and gene therapies.
Driving model-informed development (MIDD) and pharmacometrics strategies in partnership with Clinical Pharmacology, Biostatistics, Clinical and Translational teams to support regulatory and clinical decision-making.
Leading the QP evaluation of one or more assets, accountable for timely delivery of population PK/PD, exposure–response, and translational modeling analyses.
Representing QP at program and governance meetings, communicating quantitative insights clearly to non-modeling audiences.
Contributing to regulatory interactions and authoring key components of regulatory documents related to QP (e.g., IB, briefing books, etc.).
Mentoring and developing junior scientists and fostering a culture of scientific rigor and collaboration.
Identifying and implementing process improvements, new modeling approaches, and innovative quantitative tools to enhance efficiency and impact.
Ensuring analyses and documentation are of the highest scientific quality and regulatory compliance.

Requirements

What you’ll need

PhD in Quantitative Pharmacology, Pharmacometrics, Engineering, or a related field with 6+ years of post-doctoral or industry experience; or MS with 9+ years of relevant experience.
Demonstrated expertise in population PK/PD, exposure–response, or mechanistic modeling (systems biology, or QSP) using tools such as NONMEM, Monolix, Simulx, MATLAB/Simbiology and R.
Proven track record of delivering analyses supporting regulatory submissions and engaging directly with agencies (e.g., FDA, EMA, PMDA).
Hands-on experience with a broad range of quantitative and computational tools and a strong publication record.

Benefits

Comp & perks

health and wellness programs (including medical, dental, vision, life, and disability insurance)
fitness centers
401(k) company match
family support benefits
equity awards
annual bonuses
paid time off
paid leaves (e.g., military and parental leave)

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

population PK/PDexposure–response modelingmechanistic modelingsystems biologyQSPmodel-informed drug developmentpharmacometricsquantitative analysisregulatory submissionsscientific documentation

Soft Skills

leadershipcommunicationmentoringcollaborationprocess improvementscientific rigor

Certifications

PhD in Quantitative PharmacologyPhD in PharmacometricsPhD in EngineeringMS in related field