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Profluent Bio

Software Engineering Manager, Lab Informatics Platform

Profluent Bio

. Lead, mentor, and grow a software engineering team focused on lab informatics systems, scientific data infrastructure, and scientist-facing applications .

Posted 5/5/2026full-timeEmeryville • California • 🇺🇸 United StatesSeniorLead💰 $180,000 - $250,000 per yearWebsite

Tech Stack

Tools & technologies
BigQueryDjangoGoogle Cloud PlatformPostgresPython

About the role

Key responsibilities & impact
  • Lead, mentor, and grow a software engineering team focused on lab informatics systems, scientific data infrastructure, and scientist-facing applications
  • Architect and deliver the roadmap for systems that support sample tracking, assay data capture, Benchling integration, lab automation, experimental metadata, and analysis workflows
  • Design robust data models for protein engineering and gene editing experiments, including constructs, samples, reagents, cell systems, assay results, metadata, and experimental lineage across mammalian and bacterial workflows
  • Partner closely with scientists to translate complex laboratory requirements into scalable software solutions that accelerate Profluent’s design-build-test-learn cycle
  • Build and maintain backend systems, APIs, databases, data pipelines, and web applications using technologies such as Python, Django, PostgreSQL, BigQuery, GCP, and modern development workflows
  • Establish strong engineering practices across architecture, code review, testing, CI/CD, documentation, and agile delivery

Requirements

What you’ll need
  • 7+ years of software engineering experience, including at least 2 years managing or leading engineers
  • BS, MS, or PhD in Computer Science, Bioinformatics, Computational Biology, Engineering, or a related field, or equivalent experience
  • Strong technical leadership skills, with a track record of architecting and delivering production-quality software systems
  • Proficiency with Python, backend development, databases, APIs, and modern software engineering workflows
  • Experience building lab informatics systems, scientific data platforms, LIMS/ELN integrations, research software, or scientist-facing applications
  • Experience with data modeling and database design for complex scientific, operational, or experimental workflows
  • Demonstrated ability to work closely with scientists and translate ambiguous laboratory workflows into reliable software systems.

Benefits

Comp & perks
  • Competitive compensation package with equity participation
  • 401(k) with a strong employer match
  • Comprehensive benefits including health/dental/vision insurance
  • Generous PTO policy and commitment to work-life balance
  • Professional development opportunities in a cutting-edge field at the intersection of AI and biology

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Hard Skills & Tools
PythonDjangoPostgreSQLBigQueryGCPbackend developmentAPIsdata modelingdatabase designsoftware engineering workflows
Soft Skills
technical leadershipmentoringcollaborationcommunicationproblem-solvingtranslating requirementsagile deliverycode reviewtestingdocumentation
Certifications
BS in Computer ScienceMS in Computer SciencePhD in Computer ScienceBS in BioinformaticsMS in BioinformaticsPhD in BioinformaticsBS in Computational BiologyMS in Computational BiologyPhD in Computational BiologyEngineering degree