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Profluent Bio

Machine Learning Engineer

Profluent Bio

. Build robust, reproducible and user-friendly pipelines for automated model fine-tuning, alignment and evaluation .

Posted 4/27/2026full-timeEmeryville • California • 🇺🇸 United StatesMid-LevelSenior💰 $180,000 - $250,000 per yearWebsite

Tech Stack

Tools & technologies
AWSAzureCloudDockerETLGoogle Cloud PlatformKubernetesPythonPyTorch

About the role

Key responsibilities & impact
  • Build robust, reproducible and user-friendly pipelines for automated model fine-tuning, alignment and evaluation
  • Design and implement modular, easy-to-maintain, multi-model pipelines for protein design.
  • Develop highly scalable ETL pipelines to process petabyte-scale protein data for model pretraining
  • Optimize model training and inference code to maximize throughput and resource utilization when deployed at scale
  • Develop software and infrastructure that enable the ML team to work quickly and frictionlessly in distributed and multi-cloud environments
  • Partner with ML and protein design scientists to prototype research ideas and bring them into production

Requirements

What you’ll need
  • BS or MS in Computer Science, Machine Learning, or a related field
  • 3+ years of hands-on experience building and training ML models in PyTorch
  • Strong Python and software engineering fundamentals, including testing, code quality, and version control
  • Experience profiling, benchmarking, and optimizing ML model training and inference
  • Experience implementing or optimizing transformer-based architectures
  • Familiarity with cloud infrastructure and containerization (GCP, AWS, Azure, Kubernetes, Docker)
  • Strong fundamentals in ML, statistics, and/or linear algebra

Benefits

Comp & perks
  • Competitive compensation package with equity participation
  • 401(k) with a strong employer match
  • Comprehensive benefits including health/dental/vision insurance
  • Generous PTO policy and commitment to work-life balance
  • Professional development opportunities in a cutting-edge field at the intersection of AI and biology

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools
PythonPyTorchETLmodel trainingmodel inferencetransformer-based architecturesprofilingbenchmarkingoptimizationstatistics
Soft Skills
collaborationproblem-solvingcommunicationadaptabilitycreativity
Certifications
BS in Computer ScienceMS in Computer ScienceMachine Learning certification