Principal Clinical Data Engineer

Parexel

Principal Clinical Data Engineer managing complex clinical data projects at Parexel. Leading teams, ensuring data quality and compliance while fostering client and stakeholder collaboration.

Posted 7/9/2026full-timeRemote • 🇿🇦 South AfricaLeadWebsite

Tech Stack

Tools & technologies

Google Cloud PlatformSQL

About the role

Key responsibilities & impact

Manage Projects & Technology
Lead and implement Data Receipt Agreements with vendors in collaboration with cross-functional teams
Program and establish import procedures for data ingestion using SAS or alternative technologies (e.g., Workbench)
Design and implement reconciliation checks to ensure accurate data transfer
Program offline listings and custom reports to provide valuable insights on external data
Aggregate data across all sources and manage data structures, missing values, and programming errors
Review data outputs and provide strategic insights to study teams and clients
Ensure first-time quality on all deliverables
Negotiate electronic data timelines and ensure adherence through active project management
Monitor project resourcing, identify scope changes, and resolve technical issues
Coordinate and lead programming teams to successful project completion within timelines and budget
Manage deployment of data management technology for offline listing creation
Act as SME and technology owner for data management offline listing platforms
Maintain comprehensive supporting documentation in accordance with SOPs, Guidelines, and Work Instructions
Ensure traceability and regulatory compliance across all study activities
Document deviations and communicate them to project teams
Support Initiatives & Continuous Improvement
Participate in creating standards through tools (SAS macros), libraries, and processes
Develop and implement project-specific tools and improvements
Lead or drive global initiatives related to processes and new technologies
Mentor staff and provide relevant training
Assist project teams in problem resolution and technical support
Maintain and expand regulatory knowledge within the clinical research industry
Serve as point of contact for clients and internal stakeholders on electronic data matters
Participate in bid defense meetings
Independently contribute ideas on technology and data engineering to support business development

Requirements

What you’ll need

Bachelor's degree (or equivalent) in a relevant science discipline is preferred, or equivalent work experience
Advanced proficiency in at least one of the following: SQL, SAS, or R
Comprehensive knowledge of SOPs, Guidelines, Work Instructions, System Life Cycle methodologies, ICH-GCP, and applicable regulations (e.g., 21 CFR Part 11) with proven practical application
Strong experience working with at least two systems used to aggregate data in the clinical trial process (e.g., SAS, Workbench, Elluminate)
Written and oral fluency in English

Benefits

Comp & perks

Health insurance
Professional development opportunities

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

Data ManagementData Ingestion ProceduresReconciliation ChecksProgramming Error ResolutionData Structure ManagementSAS MacrosCustom ReportingProject ManagementRegulatory ComplianceTechnical Support

Soft Skills

LeadershipMentoringCommunicationCollaborationProblem Solving