Head of Chemistry

Orum Therapeutics

Head of Chemistry leading Orum Therapeutics’ ADC and degrader-conjugate chemistry platform. Managing US and Korea scientists across discovery, bioconjugation, and candidate nomination.

Posted 8/14/2026full-timeLexington • Massachusetts • 🇺🇸 United StatesLeadWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in Medicinal Chemistry, Synthetic Organic Chemistry, and Bioconjugation, with a strong focus on leadership and mentorship across cross-disciplinary teams. Proven ability to drive scientific strategy and foster a collaborative team culture in a trust-based environment.

Highest-signal resume keywords

Medicinal Chemistry ExpertiseLeadership Experience (5–10 Years)Direct Experience in ADC or Degrader ChemistryCross-Disciplinary Team LeadershipPh.D. in Organic Chemistry or Medicinal Chemistry

ATS Keywords

Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills

Synthetic Organic ChemistryBioconjugationAnalytical ChemistryLinker ChemistryCandidate NominationEmerging Technologies EvaluationAI Tools in ChemistryScientific PublicationsPatent FilingsDriving Scientific Capability

Soft Skills

Interpersonal SkillsInclusive LeadershipExcellent CommunicationMentoringTeam Culture Development

Industry Keywords

Antibody-Conjugate Payload DiscoveryCross-Functional CollaborationProgram ReviewsCandidate ReviewsTrust-Based Culture

About the role

Key responsibilities & impact

Own the strategic and scientific direction of the chemistry organization across synthetic organic chemistry, bioconjugation, and analytical chemistry
Provide hands-on technical leadership in medicinal chemistry, conjugation, and linker chemistry from early discovery through candidate nomination
Lead, mentor, and manage approximately 10 scientists across US and Korea sites
Partner cross-functionally with CMC, Biology, Clinical, BD, IP, and Project Management
Represent chemistry in program and candidate reviews and external-facing scientific discussions
Evaluate emerging technologies and AI tools relevant to chemistry
Coordinate chemistry strategy, standards, and team culture across US and Korea sites
Foster a democratic, transparent team environment through influence and group input

Requirements

What you’ll need

Strong medicinal chemistry background evidenced by relevant peer-reviewed publications and/or patent filings
5–10 years of leadership experience
Direct experience in ADC or degrader/antibody-conjugate payload discovery chemistry
Demonstrated ability to lead and mentor a cross-disciplinary team spanning synthetic organic chemistry, bioconjugation, and analytical science
Proven track record of managing both up and down within an organization
Experience driving new scientific or organizational capability
Ability to operate in a flat, trust-based culture and lead through influence
Strong interpersonal and inclusive leadership skills
Excellent communication skills across functions, US/Korea sites, and seniority levels
Ph.D. or equivalent in Organic Chemistry, Medicinal Chemistry, or a related field
U.S. citizenship or authorization to work in the U.S. (green card)
Ability to pass a background investigation

Benefits

Comp & perks

Career growth and development support for team members
Reasonable accommodations for individuals with disabilities
Equal Opportunity Employer