VP, Clinical Operations, Data Management

Orchard Therapeutics

VP of Clinical Operations leading global clinical trials and data management operations. Ensuring quality and compliance while advancing clinical development strategy within budget.

Posted 5/19/2026full-timeLondon • 🇬🇧 United KingdomLeadWebsite

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

**Key Elements and Responsibilities**
· Provide strategic and operational leadership for clinical operations and data management across programs, from study start-up through close-out, in compliance with ICH-GCP.
· Ensure the quality, integrity, and inspection-readiness of all clinical and data management activities globally.
· Drive cross-functional collaboration to deliver clinical trials on time and within budget.
· Lead planning, execution, and reporting of clinical studies, ensuring alignment on timelines, deliverables, and resources.
· Act as the primary escalation point for critical study and vendor issues.
· Oversee study budgets, timelines, resources, and financial tracking.
· Partner with Clinical Science, Biostatistics, and external vendors to ensure seamless delivery of:
o Clinical documentation
o Data management activities
· Ensure effective coordination of regulatory submissions (e.g., IRB/ethics committees, local authorities).
· Oversee data management strategy and execution, including database design, build, maintenance, and database lock activities, in alignment with biostatistics.
· Ensure robust data integrity, accurate record-keeping, and compliant archiving practices.
· Provide oversight of clinical sites, academic partners, and vendors (e.g., CROs, labs) to ensure performance, quality, and compliance.
· Build and maintain strong relationships with investigators and key opinion leaders.
· Lead, develop, and mentor high-performing teams.
· Ensure delivery of high-quality study documentation to meet program timelines.

Requirements

What you’ll need

**Experience, Skills & Knowledge**
· Extensive experience in clinical operations leadership within biotech/pharma.
· Strong clinical project and program management expertise.
· Proven track record managing CROs and external vendors.
· Solid understanding of global regulatory requirements (ICH-GCP).
· Experience managing budgets and resource planning.
· Strong problem-solving skills with the ability to operate strategically and tactically.
· Excellent leadership, communication, and stakeholder management skills.
· Ability to thrive in a fast-paced, evolving biotech environment.
· Experience in rare/orphan diseases and/or academic collaborations is a plus.
**Education **
- Bachelor’s degree in Life Sciences required.
- Advanced degree (MS, PhD, or equivalent) preferred.
- Substantial experience leading Clinical Operations and Data Management teams.
· Experience in rare disease; gene and cell therapy experience is a plus

Benefits

Comp & perks

🌐 Worldwide ❌ Jobs You've Hidden ⭐️ Saved Jobs ✅ Applied Jobs ✉️ Email Alerts 👤 Account Orchard Therapeutics Website LinkedIn All Job Openings 201 - 500 employees Founded 2016 🧬 Biotechnology 💊 Pharmaceuticals ⚕️ Healthcare Insurance 💰 $150M Post-IPO Equity on 2021-02 Biotechnology
Pharmaceuticals
Healthcare Insurance Orchard Therapeutics is a biopharmaceutical company pioneering in the development and commercialization of transformative therapies for individuals with severe genetic diseases. The company is focusing on Hematopoietic Stem Cell (HSC) gene therapy, aiming to address unmet medical needs by offering potentially curative treatment options. With a commitment to improving lives significantly impacted by genetic conditions like metachromatic leukodystrophy, Orchard Therapeutics strives to change the treatment paradigm through innovative scientific research and dedication to patients' well-being. VP, Clinical Operations, Data Management 🔥 1 hour ago 🏢🏡 London – Hybrid ⏰ Full Time 🔴 Lead 🏥 Clinical Operations Apply Now Find Hiring Managers Customize resume + cover letter Report problem ☆ Save ☑️ Mark as applied ❌ Hide 📋 Description
**Key Elements and Responsibilities**
· Provide strategic and operational leadership for clinical operations and data management across programs, from study start-up through close-out, in compliance with ICH-GCP.
· Ensure the quality, integrity, and inspection-readiness of all clinical and data management activities globally.
· Drive cross-functional collaboration to deliver clinical trials on time and within budget.
· Lead planning, execution, and reporting of clinical studies, ensuring alignment on timelines, deliverables, and resources.
· Act as the primary escalation point for critical study and vendor issues.
· Oversee study budgets, timelines, resources, and financial tracking.
· Partner with Clinical Science, Biostatistics, and external vendors to ensure seamless delivery of:
o Clinical documentation
o Data management activities
· Ensure effective coordination of regulatory submissions (e.g., IRB/ethics committees, local authorities).
· Oversee data management strategy and execution, including database design, build, maintenance, and database lock activities, in alignment with biostatistics.
· Ensure robust data integrity, accurate record-keeping, and compliant archiving practices.
· Provide oversight of clinical sites, academic partners, and vendors (e.g., CROs, labs) to ensure performance, quality, and compliance.
· Build and maintain strong relationships with investigators and key opinion leaders.
· Lead, develop, and mentor high-performing teams.
· Ensure delivery of high-quality study documentation to meet program timelines. 🎯 Requirements
**Experience, Skills & Knowledge**
· Extensive experience in clinical operations leadership within biotech/pharma.
· Strong clinical project and program management expertise.
· Proven track record managing CROs and external vendors.
· Solid understanding of global regulatory requirements (ICH-GCP).
· Experience managing budgets and resource planning.
· Strong problem-solving skills with the ability to operate strategically and tactically.
· Excellent leadership, communication, and stakeholder management skills.
· Ability to thrive in a fast-paced, evolving biotech environment.
· Experience in rare/orphan diseases and/or academic collaborations is a plus.
**Education **
- Bachelor’s degree in Life Sciences required.
- Advanced degree (MS, PhD, or equivalent) preferred.
- Substantial experience leading Clinical Operations and Data Management teams.
· Experience in rare disease; gene and cell therapy experience is a plus Apply Now 📊 Check your resume score for this job Improve your chances of getting an interview by checking your resume score before you apply. Check Resume Score 🌐 Worldwide Built by Lior Neu-ner. I'd love to hear your feedback — Get in touch via DM or support@remoterocketship.com Search Search Jobs by country Search jobs by city Search jobs by job title Search entry-level jobs Search junior-level jobs Search senior-level jobs Search jobs by tech stack Search jobs by contract type Search remote internships Search remote part-time jobs Remote jobs Anywhere in the World Companies Hiring Anywhere in the World Companies Hiring Sales People Anywhere in the World Companies Hiring Software Engineers Anywhere in the World Resources Advice Tips for finding remote jobs Interview questions and answers Resume examples Cover letter examples Post a job Affiliates Privacy policy Terms of service Job board SEO course AI Apply Copilot OpenClaw job finder Jobs by Country Remote jobs anywhere in the world (Worldwide remote jobs) Remote jobs United States Remote jobs Australia Remote jobs Brazil Remote jobs Canada Remote jobs France Remote jobs Ireland Remote jobs Germany Remote jobs Netherlands Remote jobs Spain Remote jobs UK Popular Jobs Remote data analyst jobs Remote customer support jobs Remote executive assistant jobs Remote marketing jobs Remote product designer jobs Remote product manager jobs Remote project manager jobs Remote recruiter jobs Remote sales jobs Remote software engineer jobs Jobs by Type Remote full-time jobs Remote part-time jobs Remote contract jobs Remote internship jobs Remote entry-level jobs Remote jobs with no experience required Remote junior jobs (1-3 years of experience) Digital nomad jobs Remote jobs with no degree required Freelance remote jobs Temporary remote jobs Remote jobs hiring now Stay at home mom jobs

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Hard Skills & Tools

clinical operations leadershipclinical project managementprogram managementbudget managementdata managementdatabase designregulatory submissionsdata integrityclinical documentationbiostatistics

Soft Skills

leadershipcommunicationstakeholder managementproblem-solvingcross-functional collaborationmentoringstrategic thinkingtactical executionrelationship buildingadaptability