Senior Medical Science Liaison – Gene Therapy

Orchard Therapeutics

Senior Medical Science Liaison for gene therapy at Orchard Therapeutics. Focusing on partnerships with healthcare providers and strategic medical initiatives in the Eastern United States.

Posted 5/1/2026full-timeRemote • Massachusetts • 🇺🇸 United StatesSenior💰 $170,000 - $225,000 per yearWebsite

About the role

Key responsibilities & impact

Identify, build and maintain collaborative partnerships with healthcare providers (HCP’s) and key external experts such as KOL’s and academic institutions to become a trusted scientific partner.
Provide timely, audience-appropriate information and updates to enhance the understanding of the scientific and medical value of Orchard’s programs. This includes, but is not limited to, collaboration with Market Access, Government Affairs, Diagnostics, Patient Advocacy, Clinical Development etc.
Maintain training records and deliver training updates to ensure all personnel in assigned Qualified Treatment Centers are appropriately trained according to Orchard’s SOPs and the latest Product Manual.
Develop a territory profile including Centers of Excellence, key expertise, newborn screening approaches and leaders, and market access pathways to inform medical strategy and tactical planning in collaboration with our Commercial, Diagnostic, and Patient Advocacy partners.
Gather insights from the field on data, therapeutic area, and competitive intelligence to help inform company strategies and evidence generation plans.
Build thorough operational understanding to ensure excellence in execution balanced with risk management within the boundaries of all governance processes.
Review and oversee Investigator-Sponsored Trial (IST) requests and Early Access Program (EAP) requests throughout the internal review process and any follow up requests for information.
Build effective internal partnerships through communication and collaboration across the organization with individuals from Medical Affairs, Patient Advocacy, Public Affairs, Clinical Development, Clinical Operations, Technical Operations, Market Access, Commercial, etc.
Ensure compliance with internal and external regulatory and legal guidelines.
Maintain clinical, scientific, and technical expertise in therapeutic area.
Develop strategic initiatives to support departmental goals from a field medical excellence perspective
Successfully manage at least two large cross-functional projects with demonstrated leadership and collaboration skills while successfully maintaining geographical responsibilities
Proactively seek out and demonstrate successful peer coaching of other team members
Develop US field resource materials specific to stakeholder group, disease state, and technology.
Provide strategic insights by maintaining expertise in the therapeutic area and related fields to effectively communicate scientific insights and support strategic objectives
Monitor the competitive environment for advances and trends in the therapeutic area, including new treatment management and therapies, competitive products and provide feedback to internal stakeholders on specific initiatives of competitors
Serves as peer leader to mentor and coach new or junior MSLs, supporting onboarding, training, and field excellence

Requirements

What you’ll need

Advanced Scientific / Healthcare Degree (PhD, PharmD, MD, NP, DVM, CGC or similar preferred; RN, MS, or similar with substantial experience considered)
Minimum of 5 years of experience in a scientific, clinical or MSL role within the biotech or pharmaceutical industry
Extensive experience as an MSL supporting post-approval commercial products in the field
Ability to lead and motivate team members without a direct reporting relationship including coaching and mentoring colleagues
Track record of successfully establishing relationships with health care provider thought leaders and extended clinical care teams to become a preferred point of contact and trusted resource.
Understanding of US government and industry guidelines, regulations, laws, etc., for appropriate and compliant exchange of scientific and clinical information with external stakeholders.
Experience and relevant knowledge in one or more key therapeutic areas: hematopoietic stem cell transplantation, gene therapy, and neurology/genetics (neurometabolic genetics preferred).
Experience in developing and delivering effective scientific educational materials and programs for multistakeholder/multispecialty audiences across disease states.
Strong knowledge and established network with health care providers and industry experts
Fluency in both spoken and written English
Excellent communication and presentation skills to concisely convey complex clinical and scientific information
Effective interpersonal skills and awareness of inward and outward emotional intelligence
Ability to apply technical expertise and solutions to diverse/individualized situations
Experience in achieving results, generating ideas and influencing outcomes through collaboration in a fast-paced environment.
Highly effective in building close working relationships with cross-functional partners
Growth mindset – curious by nature, proactive in keeping abreast of key scientific developments and building understanding of assigned territory
Valid US Driver’s License and clean driving record
Ability to travel frequently (75%), often overnight

Benefits

Comp & perks

🌐 Worldwide ❌ Jobs You've Hidden ⭐️ Saved Jobs ✅ Applied Jobs ✉️ Email Alerts 👤 Account Orchard Therapeutics Website LinkedIn All Job Openings 201 - 500 employees Founded 2016 🧬 Biotechnology 💊 Pharmaceuticals ⚕️ Healthcare Insurance 💰 $150M Post-IPO Equity on 2021-02 Biotechnology
Pharmaceuticals
Healthcare Insurance Orchard Therapeutics is a biopharmaceutical company pioneering in the development and commercialization of transformative therapies for individuals with severe genetic diseases. The company is focusing on Hematopoietic Stem Cell (HSC) gene therapy, aiming to address unmet medical needs by offering potentially curative treatment options. With a commitment to improving lives significantly impacted by genetic conditions like metachromatic leukodystrophy, Orchard Therapeutics strives to change the treatment paradigm through innovative scientific research and dedication to patients' well-being. Senior Medical Science Liaison – Gene Therapy Job not on LinkedIn 🔥 3 minutes ago 🍂 Massachusetts – Remote 💵 $170k - $225k / year ⏰ Full Time 🟠 Senior 😶‍🌫️ Therapist 🦅 H1B Visa Sponsor Apply Now Find Hiring Managers Customize resume for this job Report problem ☆ Save ☑️ Mark as applied ❌ Hide 📋 Description
Identify, build and maintain collaborative partnerships with healthcare providers (HCP’s) and key external experts such as KOL’s and academic institutions to become a trusted scientific partner.
Provide timely, audience-appropriate information and updates to enhance the understanding of the scientific and medical value of Orchard’s programs. This includes, but is not limited to, collaboration with Market Access, Government Affairs, Diagnostics, Patient Advocacy, Clinical Development etc.
Maintain training records and deliver training updates to ensure all personnel in assigned Qualified Treatment Centers are appropriately trained according to Orchard’s SOPs and the latest Product Manual.
Develop a territory profile including Centers of Excellence, key expertise, newborn screening approaches and leaders, and market access pathways to inform medical strategy and tactical planning in collaboration with our Commercial, Diagnostic, and Patient Advocacy partners.
Gather insights from the field on data, therapeutic area, and competitive intelligence to help inform company strategies and evidence generation plans.
Build thorough operational understanding to ensure excellence in execution balanced with risk management within the boundaries of all governance processes.
Review and oversee Investigator-Sponsored Trial (IST) requests and Early Access Program (EAP) requests throughout the internal review process and any follow up requests for information.
Build effective internal partnerships through communication and collaboration across the organization with individuals from Medical Affairs, Patient Advocacy, Public Affairs, Clinical Development, Clinical Operations, Technical Operations, Market Access, Commercial, etc.
Ensure compliance with internal and external regulatory and legal guidelines.
Maintain clinical, scientific, and technical expertise in therapeutic area.
Develop strategic initiatives to support departmental goals from a field medical excellence perspective
Successfully manage at least two large cross-functional projects with demonstrated leadership and collaboration skills while successfully maintaining geographical responsibilities
Proactively seek out and demonstrate successful peer coaching of other team members
Develop US field resource materials specific to stakeholder group, disease state, and technology.
Provide strategic insights by maintaining expertise in the therapeutic area and related fields to effectively communicate scientific insights and support strategic objectives
Monitor the competitive environment for advances and trends in the therapeutic area, including new treatment management and therapies, competitive products and provide feedback to internal stakeholders on specific initiatives of competitors
Serves as peer leader to mentor and coach new or junior MSLs, supporting onboarding, training, and field excellence 🎯 Requirements
Advanced Scientific / Healthcare Degree (PhD, PharmD, MD, NP, DVM, CGC or similar preferred; RN, MS, or similar with substantial experience considered)
Minimum of 5 years of experience in a scientific, clinical or MSL role within the biotech or pharmaceutical industry
Extensive experience as an MSL supporting post-approval commercial products in the field
Ability to lead and motivate team members without a direct reporting relationship including coaching and mentoring colleagues
Track record of successfully establishing relationships with health care provider thought leaders and extended clinical care teams to become a preferred point of contact and trusted resource.
Understanding of US government and industry guidelines, regulations, laws, etc., for appropriate and compliant exchange of scientific and clinical information with external stakeholders.
Experience and relevant knowledge in one or more key therapeutic areas: hematopoietic stem cell transplantation, gene therapy, and neurology/genetics (neurometabolic genetics preferred).
Experience in developing and delivering effective scientific educational materials and programs for multistakeholder/multispecialty audiences across disease states.
Strong knowledge and established network with health care providers and industry experts
Fluency in both spoken and written English
Excellent communication and presentation skills to concisely convey complex clinical and scientific information
Effective interpersonal skills and awareness of inward and outward emotional intelligence
Ability to apply technical expertise and solutions to diverse/individualized situations
Experience in achieving results, generating ideas and influencing outcomes through collaboration in a fast-paced environment.
Highly effective in building close working relationships with cross-functional partners
Growth mindset – curious by nature, proactive in keeping abreast of key scientific developments and building understanding of assigned territory
Valid US Driver’s License and clean driving record
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Hard Skills & Tools

scientific expertiseclinical expertisetherapeutic area knowledgeMSL experienceproject managementdata analysiscompetitive intelligenceeducational material developmentrisk managementstrategic planning

Soft Skills

leadershipcoachingmentoringcommunicationinterpersonal skillscollaborationemotional intelligencepresentation skillsrelationship buildinggrowth mindset

Certifications

PhDPharmDMDNPDVMCGCRNMSvalid US Driver’s License