Director – Cell Orchestration and Logistics

Obsidian Therapeutics

Director leading cell orchestration and logistics, driving biopharma cell therapy development. Overseeing product journey and compliance with regulatory standards.

Posted 5/14/2026full-timeBedford • Massachusetts • 🇺🇸 United StatesLead💰 $191,500 - $247,500 per yearWebsite

Tech Stack

Tools & technologies

ERP

About the role

Key responsibilities & impact

Define and lead the overall Cell Orchestration governance system, including strategic and daily management oversight to ensure the highest level of service level for patients through cycle time optimization and network allocation.
Lead the implementation of a Cell Orchestration solution to support pivotal and commercial phases.
Coordinate and execute all logistics requirements across all GMP and non GMP material transfers
Oversee logistics partners’ performance with a focus on quality, reliability, and cost-effectiveness.
Develop and manage the department’s annual logistics budget based on program goals and enrollment plans; partner with Finance to analyze variances and implement adjustments.
Establish performance metrics, KPIs, and escalation pathways to ensure operational excellence and partner accountability
Support BLA-enabling supply chain activities, including Chain of Identify and Chain of Custody strategies, shipping validation and temperature monitoring strategies.
Proactively identify, assess, and mitigate operational, quality, and organizational risks; escalate key risks and issues.
Drive continuous improvement and operational excellence culture through self-detecting and self-correcting processes and systems and instilling strong ownership and accountability
Partner with Technical Operations & Quality, Regulatory and Finance to ensure full compliance with GxP, GMP, and other regulatory requirements.
Together with the VP, Global Supply Chain, identify opportunities to leverage AI capabilities of current systems in the near term, and a mid-to-long term strategy to leverage AI into cell orchestration and logistics as our programs advance.

Requirements

What you’ll need

Bachelor's degree in Supply Chain Management, Business, Engineering, or related discipline with 12+ years of progressive experience within the biopharma industry, including experience in cell & gene therapy.
Strong knowledge of and/or direct experience in autologous cell therapy focused on Patient Supply management.
Extensive quality and compliance background in a clinical GMP operational environment, including a minimum of 5+ years in a commercial or clinical GMP environment and 3 years prior experience in Cell and Gene Therapy Cold Chain Logistics.
Extensive experience in Cell Orchestration, supply chain planning, ERP system, capacity modeling, supply network strategy, and optimization.
Expertise and track record in manufacturing and supply chain execution and oversight.
Expertise on just in time logistics.
Solid knowledge of regulatory requirements, regulatory guidance, including pharmaceutical GMPs and ICH guidance.
Cultivates collaboration, transparency, and accountability within and across teams; recognizes success requires interdisciplinary thinking and partnership.
Inspires confidence, credibility, and trust internally and externally; recognized for high integrity.
Operates with urgency. Adept at building buy-in and driving alignment within and across teams, senior leadership, and external partners.
Exceptional communication skills in verbal, written, and visual formats, and adapted to the audience.
Tenacious and resilient – has navigated significant challenges (scientific and business) and is not easily daunted.
Excellent organizational skills; able to manage multiple tasks of varying degrees of complexity in parallel.
Remains calm under pressure and leads others through complex situations.
Seeks the data, information, and support needed (internally and externally) to make efficient and informed decisions and meet objectives.
Builds followership by being transparent, persuasive, excited about the work, and willing to work hard together to get the job done.
Continuous learner – actively follows innovations in area of expertise, fosters innovative thinking, and adopts novel approaches that are fit for purpose.
Reflective and self-aware; leads by example with a growth mindset.

Benefits

Comp & perks

comprehensive medical, dental, and vision coverage
company contributions to health savings and retirement accounts
ample paid time off
access to wellness programs
rich career growth opportunities

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

Cell Orchestrationsupply chain planningERP systemcapacity modelingsupply network strategyjust in time logisticsquality complianceGMPBLA-enabling supply chain activitiestemperature monitoring strategies

Soft Skills

collaborationtransparencyaccountabilitycommunicationorganizational skillsresiliencedecision-makingleadershipinnovationgrowth mindset