Senior Director, Clinical Operations – Autoimmune

Janux Therapeutics

Senior Director leading global clinical operations for innovative T-cell engager therapies in oncology or immunology. Responsible for strategic alignment and efficient program management in a fast-paced environment.

Posted 5/7/2026full-timeSan Diego • 🇺🇸 United StatesSenior💰 $245,000 - $260,000 per yearWebsite

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Provide global operational leadership overseeing complex clinical programs focusing on innovative T-cell engager therapies for oncology or immunology indications.
Responsible for efficient planning, resourcing and execution of portfolio level programs in adherence to ICH-GCP, FDA regulations, and company SOPs.
Report into the Vice President, Clinical Operations ensuring strategic alignment of programs and key stakeholder management.
Mentor and grow the Clinical Operations team and culture to ensure successful program delivery.

Requirements

What you’ll need

Bachelor’s degree in life sciences or related field with 12+ years of experience in clinical research, including at least 10 years in clinical trial management. Advanced degree preferred.
Strong experience in complex autoimmune indications, early phase experience strongly preferred.
Ability to define strategy and ensure organizational goals are executed in global clinical operations plans.
Proven track record of leading complex clinical programs from start to completion.
Strong knowledge of ICH GCP, FDA regulations, and global clinical regulatory guidelines.
Strong IT skills in MS Office and clinical trial systems (e.g., CTMS, eTMF, EDC).
Expertise in clinical budgeting and efficient allocation of resources
Demonstrated success in leading, mentoring, developing diverse clinical teams and providing oversight to CROs.
Excellent communication, leadership, and interpersonal skills, including the ability to understand and present technical information effectively to executive leadership.
Strong organizational and time management abilities.
High level of accountability, adaptability, and attention to detail with an ability to set priorities and handle multiple tasks simultaneously in a changing environment.
Ability to work independently and collaboratively in a fast-paced, matrixed environment.

Benefits

Comp & perks

Annual bonus program
Incentive stock option plan
401k plan with flat non-elective employer contribution
Comprehensive medical insurance with 90-100% employer-paid premiums
Dental and vision insurance
HSA, FSA, and supplemental insurance plans (life, disability, accident, critical illness, hospital indemnity)
Unlimited PTO
Generous holiday schedule; includes summer and winter company shutdown
Relocation assistance

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Hard Skills & Tools

clinical researchclinical trial managementclinical budgetingT-cell engager therapiesautoimmune indicationsICH GCPFDA regulationsglobal clinical regulatory guidelinesportfolio managementresource allocation

Soft Skills

leadershipmentoringcommunicationinterpersonal skillsorganizational skillstime managementaccountabilityadaptabilityattention to detailstrategic alignment