Senior Director, Clinical Operations

Jade Biosciences

Senior Director of Clinical Operations overseeing clinical programs for a biotechnology firm tackling autoimmune diseases. Leading strategy, vendor management, and cross-functional collaboration.

Posted 6/26/2026full-timeRemote • California, Illinois, Massachusetts, Washington • 🇺🇸 United StatesSenior💰 $255,000 - $280,000 per yearWebsite

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Acts as Clinical Operations program lead for assigned program(s)
Represents Clinical Operations at the Clinical Development Team and/or Global Program Team
Develops and executes program operational strategy
Partners closely and effectively with other functions and functional heads to drive program forward
Provides strategic and technical recommendations to senior leadership
Directs the selection of CROs and other vendors (IxRS, Central Lab, ancillary/tech vendors)
Acts as an escalation point for CRO/vendor issues
Directs development of vendor Scopes of Work (SOW), scope changes, budgets, and vendor payments
Partners with CRO and other vendors to deliver on study execution
Creates and tracks clinical program budgets
Directs risk mitigation, escalation, and resolution activities both internally as well as with sites and vendors
Directs technical and strategic input into the development of clinical documents (protocols, monitoring plans, informed consent forms, investigator brochures, clinical study reports, etc.)
Builds relationships with clinical sites, vendors, and key stakeholders
Maintains understanding of external landscape and adjusts plans accordingly
Represents Clinical Operations in cross-functional activities as assigned
Plays a key role in the development and management of the Clinical Operations function; may act as a deputy for the Head of Clinical Operations as assigned
Hires, manages, coaches, and mentors staff
Contributes to building the organization.

Requirements

What you’ll need

Bachelor's degree in a related field required, an advanced degree is a plus
17+ years of clinical research experience, including 10+ years of trial and/or program-level management within a biopharmaceutical company, and 3+ years of line management experience
Exceptional clinical trial & program management skills with a focus on strategic oversight of program execution on time and on budget
Extensive experience selecting and managing vendors, including CROs, labs, IxRS, EDC, and ancillary technology/applications (e.g. eDiaries, eConsent, apps, etc)
Thorough knowledge and understanding of FDA and ICH Guidelines, GCP, medical terminology, and clinical trials
Detailed understanding of all aspects of clinical protocol design, implementation, IND/BLA/NDA submissions, and overall drug development
Experience managing, coaching, and mentoring personnel
Excellent communication, organizational, negotiation, and interpersonal skills with a strong reputation for collaboration
Able to drive decisions forward in times of ambiguity or with incomplete information
Effective in promoting and maintaining productive internal and external relationships
Proven leadership and team building skills, along with success in proactive risk mitigation and problem solving
Flexible and creative to meet the needs and challenges of a growing, dynamic company
Demonstrated problem solving abilities
Proven ability to influence up, down, and across the organization
Strong financial acumen with outstanding track record of building budgets and managing expenses to budget
Study coordinator and/or site monitoring experience a plus
Thrives in a small company environment, where day-to-day duties go above and beyond this job description
May contribute to corporate activities, e.g. preparation for Board of Director meetings.

Benefits

Comp & perks

As part of the I-9 verification of authorization to work in the United States, Jade Bioscience participates in E-Verify. To learn more about E-Verify please review this poster.
Jade Biosciences is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

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Hard Skills & Tools

clinical trial managementprogram managementvendor managementclinical protocol designIND submissionsBLA submissionsNDA submissionsrisk mitigationbudget managementclinical document development

Soft Skills

communicationorganizational skillsnegotiationinterpersonal skillsleadershipteam buildingproblem solvingcollaborationflexibilitycreativity