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Gilead Sciences

Executive Director – Viral Vector Process Development

Gilead Sciences

Leading viral vector development and manufacturing support for cancer therapies at Kite. Overseeing technical strategy and cross-functional collaboration for optimized vector platforms.

Posted 7/15/2026full-timeSanta Monica • California • 🇺🇸 United StatesLead💰 $255,425 - $330,550 per yearWebsite

Core Competencies

Role fit
Core Competencies

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Demonstrates expertise in viral vector development and manufacturing support, with a focus on lentiviral vector design, process development, and technology transfer for cell and gene therapy. Proven ability to lead cross-functional teams and drive innovations in vector productivity and robustness.

Highest-signal resume keywords
Viral Vector DevelopmentLentiviral Vector DesignProcess DevelopmentTechnology TransferCell Therapy Programs

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills
Viral Vector ManufacturingTransgene OptimizationUpstream Production SystemsDownstream PurificationAnalytical Characterization StrategiesCell Performance OptimizationCMC SustainabilityConstruct ArchitecturePromoter SelectionProcess Scale-Up
Soft Skills
LeadershipCollaborationCross-Functional Team Management
Certifications & Qualifications
PhD in Biochemical EngineeringPhD in Molecular BiologyPhD in VirologyMS in Related Field
Industry Keywords
Gene TherapyCell TherapyCAR-TViral Vector PlatformsManufacturing ReadinessTech TransfersEmerging Delivery TechnologiesLife Cycle ManagementProductivity ImprovementRobustness

About the role

Key responsibilities & impact
  • Accountable for technical strategy for viral vector platforms across clinical and commercial scale, including complex tech transfers, external manufacturing partnerships, and late-stage manufacturing readiness.
  • Provide deep expertise in lentiviral vector (LVV) design, including construct architecture, promoter selection, and transgene optimization
  • Lead viral vector process development, including: Upstream production systems (transient and stable), Downstream purification and recovery operations
  • Drive process scale-up and technology transfer to clinical and commercial manufacturing sites (internal and external)
  • Oversee LVV life cycle management and manufacturing support capabilities
  • Lead initiatives to improve viral vector productivity, robustness, and cost of goods
  • Advance next-generation capabilities, including: In vivo viral vector development, Platform innovations and emerging delivery technologies
  • Ensure viral vector development decisions are optimized across the full cell therapy value chain, from transduction efficiency and cell performance to manufacturing robustness and CMC sustainability.
  • Partner closely with: Research to translate early concepts into developable and scalable vector designs, T cell process development to align vector performance with cellular outcomes, Analytical development to ensure appropriate characterization and control strategies.

Requirements

What you’ll need
  • PhD in Biochemical Engineering, Molecular Biology, Virology, or related field with 15+ years of experience (or MS with 18+ years)
  • Extensive experience in viral vector development and manufacturing support for cell and/or gene therapy
  • Demonstrated expertise in LVV and/or RVV systems
  • End-to-end experience from early development through commercialization
  • Strong understanding of: Viral vector development across phases, Analytical characterization strategies, Manufacturing and tech transfer considerations for viral vector
  • Experience leading cell therapy programs (e.g., CAR-T)
  • Proven ability to lead in a highly matrixed, cross-functional environment

Benefits

Comp & perks
  • company-sponsored medical, dental, vision, and life insurance plans
  • paid time off
  • discretionary annual bonus
  • discretionary stock-based long-term incentives