Clinical Trial Manager

Frontier Medicines

Clinical Trial Manager overseeing the execution of oncology clinical trials for Frontier Medicines. Supporting study execution, CRO management, and cross-functional collaboration in a hybrid role.

Posted 7/29/2026full-timeBoston • Massachusetts • 🇺🇸 United StatesMid-LevelSenior💰 $120,000 - $150,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

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Demonstrates expertise in managing clinical trials, including oversight of CROs, regulatory compliance, and study performance metrics. Proficient in vendor management and maintaining inspection readiness while ensuring adherence to ICH-GCP guidelines.

Highest-signal resume keywords

Clinical Trial ManagementOncology Study SupportVendor ManagementICH-GCP GuidelinesRegulatory Compliance

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Trial ManagementRegulatory Document ReviewStudy Performance MonitoringBudget TrackingProtocol Review

Soft Skills

Organizational SkillsProblem-Solving SkillsTime Management SkillsWritten CommunicationVerbal Communication

Tools & Technologies

Clinical Operations TrackersDocument RepositoriesClinicalTrials.gov

Industry Keywords

Clinical TrialsCRO ManagementOncologyInspection ReadinessStudy Closeout

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Support day-to-day activities within one or more clinical trials, including country/site feasibility assessments, site selection, start-up, maintenance, and close-out.
Serve as a key operational point of contact for CROs and trial sites, identifying and escalating potential issues as needed.
Assist with oversight of CRO and vendor set-up, liaising with CROs to ensure timely study initiation.
Review site-level regulatory documents (e.g., Informed Consent Forms, essential documents) and escalate to appropriate stakeholders as needed.
Help ensure inspection readiness, TMF quality, and adherence to protocol and regulatory requirements.
Proactively identify potential operational challenges and, in partnership with senior team members, propose mitigation plans to keep study execution on track.
Assist with review of protocols, master template informed consent forms, case report forms, and other clinical study documents as needed.
Monitor study performance metrics, timelines, and deliverables, and review CRO trip reports for trends and quality issues.
Track study budgets and vendor invoices/change orders in partnership with Clinical Operations and Finance, flagging discrepancies as needed.
Help maintain timely and accurate study registration and updates on ClinicalTrials.gov and other applicable registries.
Coordinate Clinical Trial Team meetings and drive action item follow-up.
Maintain clinical operations trackers, databases, and document repositories.
Provide regular study updates to internal stakeholders and support enrollment, database lock, and study closeout activities.

Requirements

What you’ll need

Bachelor's degree in a scientific, healthcare, or related field, or an RN, required.
3-4 years of Clinical Trial Manager or Clinical Project Management experience, ideally supporting oncology clinical trials.
Experience supporting oncology studies strongly preferred.
Vendor and CRO management experience.
Strong working knowledge of ICH-GCP guidelines and clinical trial regulations.
Excellent organizational, problem-solving, and time management skills, with strong attention to detail.
Strong written and verbal communication skills with a collaborative, team-oriented approach.
Comfortable in a fast-paced, dynamic environment; a proactive, roll-up-your-sleeves mindset.
Legally authorized to work in the United States.

Benefits

Comp & perks

Health Care Plan (Medical, Dental & Vision)
Retirement Plan (401k, IRA)
Life Insurance (Basic, Voluntary & AD&D)
Paid Time Off (Vacation, Sick & Public Holidays)
Family Leave (Maternity, Paternity)
Short Term & Long Term Disability
Training & Development
Free Food & Snacks
Wellness Resources
Stock Option Plan