Senior Bioinformatics Engineer

DNAnexus

Sr. Bioinformatics Engineer developing scalable frameworks for genomic and multi-omic data processing at DNAnexus.

Posted 5/13/2026full-timeRemote • CzechiaSeniorWebsite

Tech Stack

Tools & technologies

Python

About the role

Key responsibilities & impact

Design and develop distributed data models, storage schemas, and query engines optimized for genomic and multi-omic data at scale on the DNAnexus Platform.
Build scalable, production-grade framework components for the DNAnexus Platform to support genomic and multi-omic analytical workflows.
Share bioinformatics knowledge within the team of engineers for the purpose of building a product together within a team.
Stay current with the latest advancements in bioinformatics data management and analytics to drive platform innovation.

Requirements

What you’ll need

5+ years of professional experience in software development in Python, in a bioinformatics or life science context.
Experience performing large-scale genomic association, burden, and polygenic analyses (e.g., with REGENIE, SAIGE), including upstream data preparation, quality control, and cohort construction.
Working knowledge of clinical genomics workflows, including EHR and FHIR-based genomic data exchange preferable.
Excellent communication and collaboration skills to work effectively with cross-functional teams (scientists, product managers, engineers).
Bioinformatics knowledge and ability to work with engineers to translate the research concepts into a newly developed solution.

Benefits

Comp & perks

Employees can work remotely

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

Pythongenomic association analysisburden analysispolygenic analysisdata preparationquality controlcohort constructionbioinformaticsclinical genomics workflowsdata management

Soft Skills

communicationcollaborationteamworkknowledge sharingcross-functional teamwork