Senior Staff, Software Engineer

Delfi Diagnostics

Senior technical leader to define and implement architecture for bioinformatics pipeline systems at DELFI Diagnostics. Collaborate extensively across teams to execute strategies for health solutions.

Posted 5/13/2026full-timePalo Alto • California • 🇺🇸 United StatesSenior💰 $185,000 - $260,000 per yearWebsite

Tech Stack

Tools & technologies

AWSCloudCyber SecurityJavaPythonRustSDLC

About the role

Key responsibilities & impact

Set long-term technical strategy and architectural vision for our bioinformatics pipeline systems
Lead system architecture and high-stakes design reviews end-to-end, guiding the team through the most complex technical tradeoffs
Design and own data hand-off and integration architecture between software systems
Serve as a leader in engineering best practices—establishing standards, driving software-development lifecycle (SDLC) rigor
Drive requirements engineering, risk analysis, and verification strategies for regulated software components
Architect and own the DevOps strategy for the pipeline team, including cybersecurity, CI/CD, infrastructure-as-code
Mentor and develop staff and senior engineers, raising the team's technical ceiling

Requirements

What you’ll need

Bachelor's degree in Computer Science, Mathematics, Data Science, or related field
BS: 10+ years, MS: 8+ years, Ph.D: 5+ years
Excellent verbal and written communication skills, including proficiency in public speaking and technical presentation
Exposure to the life sciences industry, including DNA sequencing, quantitative genetics, bioinformatics, or data science
Demonstrated experience setting long-term technical strategy and architectural standards across multi-team or multi-system scope
Advanced knowledge of cloud computing infrastructure design and implementation for scalable high-performance computing applications (AWS preferred)
Expertise in Python and strong proficiency in at least one compiled language (Rust, Java, C++, or C#)
Strong software design skills
Experience designing data integration patterns and contracts between software systems
Strong command of agile development practices, Jira, Git, and modern CI/CD pipelines

Benefits

Comp & perks

flexible time-off policy
401(k) retirement plan
competitive medical, dental, and vision coverage
onsite lunch 3 days a week
other wellness related offerings

ATS Keywords

✓ Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills & Tools

PythonRustJavaC++C#cloud computingdata integrationsoftware designDevOpsagile development

Soft Skills

leadershipcommunicationmentoringtechnical presentationrequirements engineeringrisk analysisverification strategies