Principal Application Security Engineer – AI & Agentic Systems

CVS Health

Principal Application Security Engineer securing AI and application systems at CVS Health. Leading secure design practices and mentoring engineers to enhance security maturity.

Posted 5/19/2026full-timeRemote • New York • 🇺🇸 United StatesLead💰 $144,200 - $288,400 per yearWebsite

Tech Stack

Tools & technologies

AWSAzureCloudGoGoogle Cloud PlatformJavaJavaScriptPython

About the role

Key responsibilities & impact

Lead development and enforcement of application and AI security policies, standards, and guardrails
Establish secure design patterns for AI agent frameworks
Promote organization-wide awareness of AI-specific risks such as model misuse, prompt injection, data leakage, and unsafe agent behavior
Serve as the principal SME for securing AI-enabled applications and agentic system architectures
Architect and review secure designs for systems leveraging LLMs/foundation models, autonomous and semi-autonomous agents, RAG pipelines, and tool-using or decision-making workflows
Define identity, authorization, data access, and observability controls specific to agentic environments
Influence engineering and product teams to integrate secure engineering practices and align security with compliance, privacy, and responsible AI initiatives
Advise senior leadership on AI security implications, architectural decisions, and long-term strategy
Lead advanced security testing and risk assessments for AI-enabled systems
Provide senior technical leadership during incidents involving application or AI systems
Mentor senior and principal engineers to elevate security maturity across the organization

Requirements

What you’ll need

10+ years of experience designing, building, and securing large-scale applications and platforms
7+ years of expertise in application security, including threat modeling, secure design, and vulnerability management
7+ years of programming experience in one or more languages such as Python, Java, JavaScript, C#, or Go
5+ years of experience of developing and securing AI and ML workloads, with recent experience in generative AI and agentic workloads
5+ years of experience public cloud platforms (AWS, Azure, and/or GCP) and modern application architectures
3+ years of experience with containerized, serverless, and microservice-based architectures

Benefits

Comp & perks

medical, dental, and vision coverage
paid time off
retirement savings options
wellness programs
comprehensive benefits package designed to support the physical, emotional, and financial well-being of colleagues and their families

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

application securitythreat modelingsecure designvulnerability managementprogramming (Python)programming (Java)programming (JavaScript)programming (C#)programming (Go)AI and ML workload security

Soft Skills

leadershipmentoringinfluencingcommunicationstrategic advising