Clinical Trial Manager

Climb Bio

Clinical Trial Manager leading Phase 1–2 clinical trials for Climb Bio, a biotechnology company developing immune-disease therapeutics. Owning study operations, CRO execution, compliance, and inspection readiness.

Posted 8/21/2026full-timeRemote • Massachusetts • 🇺🇸 United StatesMid-LevelSenior💰 $132,000 - $175,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in leading clinical trial operations, with a strong focus on Phase 1 and Phase 2 execution, regulatory compliance, and quality management. Proven ability to manage cross-functional teams and external partnerships while ensuring adherence to GCP and SOP standards.

Highest-signal resume keywords

Clinical Trial ManagementGCP GuidelinesRegulatory RequirementsStudy Strategy ExecutionRisk Assessment

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills

Clinical Research ProcessesPhase 1–3 Trial ManagementDocumentation DisciplineInspection ReadinessBudget Tracking

Soft Skills

Excellent CommunicationInterpersonal SkillsAnalytical AbilitiesProblem-SolvingAttention to Detail

Tools & Technologies

MS Suite

Industry Keywords

Clinical OperationsCRO ManagementStudy StartupQuality StandardsCAPA

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Lead end-to-end delivery of clinical trials, with immediate emphasis on owning Phase 1 execution and supporting Phase 2 execution
Serve as the Clinical Operations representative on study teams
Lead study-level operational execution in partnership with Clinical Development, Regulatory, Data Management, Safety, Statistics, and CMC
Drive alignment and issue resolution
Collaborate with Senior Clinical Trial Managers on complex studies and grow into greater study ownership
Own clinical trial conduct, study-level inspection readiness, TMF health, documentation discipline, investigational product supply, and regulatory submissions support
Conduct proactive study-level risk assessment, prioritization, and escalation
Partner with senior Clinical Operations leadership on study strategy and execution, issue solving, and inspection-ready operational approaches
Support study startup and ongoing management in alignment with GCP, SOPs, and quality standards
Lead study-level operational activities during audits and regulatory inspections, including preparation, inspection support, responses, and CAPAs
Lead CRO and vendor execution, with accountability for quality, timelines, and budget performance
Track clinical expenses and budgets with senior team members
Prepare timely, accurate trial status reports for leadership

Requirements

What you’ll need

Bachelor’s degree
Minimum of 3 years of experience independently managing clinical trials across Phases 1–3
At least 2 years in a biotech managing studies through start-up and maintenance stages
Working knowledge of clinical research processes, GCP guidelines, and regulatory requirements
Excellent communication and interpersonal skills, with a focus on managing external relationships effectively
Proficiency in MS Suite
Ability to travel occasionally, approximately 20%
Strategic planning and organizational skills
Analytical and problem-solving abilities
Ability to work effectively with external partners in a dynamic, fast-paced environment
Attention to detail and commitment to quality
Ability to connect decisions to data integrity and compliance
Ability to influence and mentor others in quality behaviors

Benefits

Comp & perks

Discretionary annual bonus
Medical, Dental and Vision benefits
Short-term and long-term disability
Company paid basic life insurance
401k company match
Generous paid time off
Paid holidays
Stock options
Remote or hybrid work option