Associate Director – Medical Director, Clinical Development

Climb Bio

Clinical lead in clinical development at Climb Bio, advancing therapeutics for immune-mediated diseases. Collaborating cross-functionally to enhance clinical strategy and execution.

Posted 6/17/2026full-timeWellesley Hills • Massachusetts • 🇺🇸 United StatesSenior💰 $187,500 - $254,000 per yearWebsite

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Serve as a clinical lead within the development organization
Contribute to the development and execution of Clinical Development Plans (CDPs) aligned with the Target Product Profile (TPP) and regulatory requirements
Support study design, including protocol development, endpoints, and statistical considerations
Translate clinical and emerging data into actionable insights to inform program strategy
Partner with Clinical Operations to ensure high-quality study execution and achievement of key milestones
May serve as Medical Monitor, overseeing patient safety, safety signal detection, and benefit-risk assessment
Provide medical oversight of CROs, investigators, and study teams
Contribute to preparation of regulatory submissions (e.g., IND/CTA, briefing documents, responses to health authorities)
Participate in interactions with regulatory agencies, key opinion leaders (KOLs), and advisory boards
Represent the company at investigator meetings, site initiations, and scientific conferences
Partner with Non-clinical development, Clinical Pharmacology, Clinical Operations, Regulatory, and Data Science teams to support program development and data interpretation
Support internal governance discussions and program decision-making
Contribute to the authorship of clinical documents (protocols, IBs, CSRs) and scientific publications (abstracts, posters, manuscripts)
Develop and deliver training materials for CROs, CRAs, and study sites

Requirements

What you’ll need

MD (or international equivalent) required
Board certification in Nephrology (or Internal Medicine with nephrology subspecialty training) strongly preferred
Deep understanding of nephrology, including diseases such as IgA nephropathy, membranous nephropathy, and other immune-mediated kidney diseases
Experience with clinical trial methodology, GCP/ICH, and regulatory requirements (FDA, EMA, etc.)
Experience in early- and/or late-stage clinical development preferred
Strong collaboration skills in a matrixed environment
Ability to synthesize complex data and communicate clearly to diverse audiences
High accountability, adaptability, and comfort in a fast-paced, small-company setting
Patient-focused, science-driven, and aligned with a high-performance culture.

Benefits

Comp & perks

discretionary annual bonus
comprehensive benefits to include Medical, Dental and Vision
Life & Disability
401k company match
generous paid time off
equity

ATS Keywords

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Hard Skills & Tools

clinical development plansprotocol developmentstatistical considerationsregulatory submissionsclinical trial methodologyGCPICHnephrologydata interpretationclinical documents

Soft Skills

collaborationcommunicationaccountabilityadaptabilitypatient-focusedscience-drivenhigh-performance culture

Certifications

MDboard certification in nephrology