Clinical Trial Manager

Caribou Biosciences

Clinical Trial Manager overseeing global CRISPR cell-therapy trials at Caribou Biosciences. Managing CROs, vendors, data quality, regulatory compliance, and study execution from start-up through close-out.

Posted 8/5/2026full-timeRemote • California • 🇺🇸 United StatesMid-LevelSenior💰 $160,000 - $175,000 per yearWebsite

Core Competencies

Role fit

Core Competencies

Use this summary to align your resume positioning with the role.

Demonstrates expertise in managing clinical trial operations, including study planning, execution, and oversight, while ensuring compliance with regulatory requirements. Proficient in coordinating cross-functional teams and maintaining high-quality documentation and communication throughout the clinical study lifecycle.

Highest-signal resume keywords

Clinical Trial ManagementRegulatory Compliance (ICH-GCP, FDA, EMA)Microsoft 365 ProficiencyRisk Assessment and MitigationSponsor Oversight

ATS Keywords

Tailor your resume

Applicant Tracking System Keywords

Tip: use these terms in your resume and cover letter to boost ATS matches.

Hard Skills

Clinical OperationsStudy PlanningSite MonitoringTrial ExecutionDocumentation PracticesData ReviewProtocol Deviation ReviewOperational Risk ManagementInvestigational Product LogisticsPhase III Clinical Trials

Soft Skills

Attention to DetailExcellent CommunicationInterpersonal SkillsOrganizational SkillsTeam Collaboration

Tools & Technologies

Trial Master FileStudy ToolsTimelinesTrackersMicrosoft WordMicrosoft ExcelMicrosoft PowerPointMicrosoft OutlookMicrosoft SharePoint

Industry Keywords

Cell TherapyOncologyClinical StudiesCRO PerformanceGlobal Regulatory Requirements

Tech Stack

Tools & technologies

Google Cloud Platform

About the role

Key responsibilities & impact

Manage operational activities across all phases of clinical studies, including feasibility, start-up, maintenance, and close-out
Support study planning and execution, including site and vendor identification, evaluation, qualification, and oversight
Implement operational strategies supporting patient enrollment, site monitoring, and trial execution
Manage clinical trial operations from study start-up through Clinical Study Report completion
Develop and manage study tools, documentation, timelines, trackers, communications, and key study documents
Identify, assess, track, mitigate, and document trial-level operational risks
Organize study meetings, agendas, minutes, presentations, and action items
Provide Sponsor oversight of CRO and vendor performance, deliverables, metrics, and governance
Coordinate investigational product, laboratory, sample management, and study supply logistics
Perform ongoing Sponsor data review, query management, protocol deviation review, safety review, and issue resolution
Review monitoring reports and participate in monitoring or oversight visits as appropriate
Maintain the Trial Master File and inspection readiness
Review or approve site-specific documents, including informed consent forms, site budgets, and monitoring reports
Support audits, inspections, investigator and site training, process improvements, and strategic initiatives
Provide trial updates, operational risks, and mitigation strategies to stakeholders
Collaborate with Clinical Development, Data Management, Biostatistics, Regulatory Affairs, Medical Monitoring, Drug Supply, Quality Assurance, Safety, and other cross-functional partners

Requirements

What you’ll need

BS degree in the life sciences with a minimum of 6+ years in Clinical Operations, or MS degree in the life sciences with a minimum of 4+ years of Clinical Operations experience
3 years of Sponsor Clinical Trial Management experience
Experience supporting complex global Phase III clinical trials
Cell therapy or oncology experience
Strong understanding of ICH-GCP, FDA, EMA, and applicable global regulatory requirements
Demonstrated proficiency in technology use, documentation practices, and sound business acumen
Advanced proficiency in Microsoft 365, including Word, Excel, PowerPoint, Outlook, and SharePoint
Strong attention to detail and commitment to high-quality work
Excellent written and verbal communication and interpersonal skills
Ability to travel up to 20% based on business needs
Legal authorization to work in the United States

Benefits

Comp & perks

Comprehensive compensation package including competitive salary, bonus, and equity
Salary range of $160,000–$175,000
Generous paid vacation time
Company-observed holidays
Medical insurance
Dental insurance
Vision insurance
401(k) retirement savings plan with matching employer contributions
Employee stock purchase plan (ESPP)
Tuition reimbursement program