Associate Director, Inflammation Biology

Apogee Therapeutics

Associate Director leading a team in I&I biology research at a clinical-stage biotechnology company. Focus on therapeutic development through innovative antibody mechanisms.

Posted 6/2/2026full-timeRemote • Massachusetts • 🇺🇸 United StatesSenior💰 $185,000 - $205,000 per yearWebsite

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Hard Skills

biologypharmacologyin vitro modelsex vivo modelsdata analysisregulatory submissionsproject managementCRO managementassay platformscytokine release assays

Soft Skills

strategic visioncommunicationcollaborationproject coordinationdata interpretationleadershiptime managementproblem-solvingadaptabilitymentoring

Tools & Technologies

ELISAMSDflow cytometrydata sets analysislaboratory best practicesCRO evaluationtherapeutic antibodiescell typesdisease mechanismsresearch publications

Certifications & Qualifications

Ph.D.

Industry Keywords

I&I disease biologyatopic dermatitisallergic asthmaEoEinflammatory cytokineschemokinestherapeutic developmentfunctional modelsscientific researchjunior scientist development

About the role

Key responsibilities & impact

Apply deep expertise in biology and pharmacology to provide strategic scientific vision and guide therapeutic I&I biology research across atopic dermatitis, allergic asthma, EoE, and other I&I indications.
Design, develop, and oversee disease-relevant and complex in vitro and ex vivo models using multiple primary human cell types to evaluate the mechanism of action of Apogee antibodies and target biology.
Contribute to authoring and reviewing regulatory submissions and publications.
Manage and coordinate projects (in-house & CRO) to ensure adherence to timelines and goals.
Establish and promote laboratory best practices.
Analyze and interpret complex data from studies to inform on program decisions and effectively communicate outcomes and recommendations to the research group and senior leaders.
Collaborate with scientists across functions to generate high-quality data supporting programs from discovery through development.

Requirements

What you’ll need

Ph.D. degree and a minimum of 8 years of scientific/technical experience.
Broad understanding of I&I disease biology (atopic dermatitis, asthma, and EoE) and underlying disease mechanisms is required and familiarity with inflammatory cytokine/chemokine networks is strongly preferred.
Hands-on expertise developing and validating complex in vitro and ex vivo functional models using disease relevant cell types
Proficiency with analysis of large, cross-platform data sets and assay platforms such as ELISA/MSD, flow cytometry, and cytokine/mediator release assays to characterize and advance therapeutic antibodies and target biology.
Ability to manage multiple projects with competing timelines and shifting priorities simultaneously.
CRO management experience including evaluation of new CROs is desired.
Experience managing and developing junior scientists.

Benefits

Comp & perks

A great culture, grounded in our C.O.R.E. values: Caring, Original, Resilient and Egoless
Opportunity to work in a fast-paced, highly dynamic environment where you help shape the culture and company, wear multiple hats, and learn quickly
Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits
We provide competitive time off, including three weeks PTO, two one-week company-wide shutdowns a year and dedicated paid sick leave
Commitment to growing you professionally and providing access to resources to further your development
Apogee offers regular all team, in-person meetings to build relationships and problem solve