Director, AI Enablement

Apogee Therapeutics

Director of AI Enablement at Apogee Therapeutics shaping and executing AI strategy across the enterprise. Leading the adoption and governance of advanced AI capabilities in a dynamic and clinical-focused environment.

Posted 5/19/2026full-timeRemote • 🇺🇸 United StatesLead💰 $225,000 - $250,000 per yearWebsite

Tech Stack

Tools & technologies

Cyber Security

About the role

Key responsibilities & impact

Own end-to-end execution of the AI Enablement Program: working group facilitation, use case pipeline management, adoption tracking, and executive reporting
Drive AI literacy and responsible use across a diverse workforce, meeting employees where they are and building capability without coercion
Design and deliver training and engagement programs calibrated to varied audience profiles and functional contexts
Manage the use case intake pathway from submission through scoring, cross-functional review, and outcome documentation
Coordinate with external AI strategy and implementation partners to maintain an integrated, non-duplicative delivery pipeline
Partner with Cybersecurity on AI tool security reviews, access control requirements, audit logging, and risk response protocols
Collaborate with Legal and Compliance on data privacy, IP risk, MNPI controls, and contractual obligations across AI deployments
Work with Data Engineering & Analytics to align AI tools with the enterprise data platform and govern data access across regulated and non-regulated environments
Engage Clinical Operations, Regulatory Affairs, and Medical teams to surface, prioritize, and advance AI use cases in trial and submission workflows
Partner with Finance, HR, Commercial, and G&A leadership on non-clinical use case discovery and deployment
Facilitate the AI Working Group, maintaining cross-functional accountability and structured deliberation on tool assessments and program priorities
Serve as the enterprise administer on the AI and agent tool landscape, owning tool selection, lifecycle management, and the capability roadmap across LLM platforms, agentic workflows, productivity tools, and clinical AI applications
Evaluate net-new tools and agentic frameworks through the governance assessment pathway before deployment; maintain the approved tool inventory with current risk classifications
Manage vendor relationships, contract terms, and licensing decisions in coordination with Finance, Legal, and Procurement
Stay ahead of capability shifts in the agent ecosystem and proactively surface opportunities.
Administer the AI Governance Framework: Approved Systems Registry, risk classification tiers, and GxP and non-GxP assessment pathways
Ensure AI deployments meet applicable regulatory, privacy, and data integrity standards, and support audit readiness across GxP-adjacent environments
Evolve governance controls as the tool landscape and regulatory environment change.
Define and own program success metrics, such as adoption rates, use case throughput, time-to-assessment, literacy baselines, and quantified efficiency gains by function
Establish a reporting cadence to leadership and the Governance Committee with clear narrative on program ROI and risk posture
Maintain a use case outcomes repository to capture lessons learned and identify replication opportunities across the organization
Benchmark Apogee’s AI maturity against clinical-stage biotech peers and industry best practice to prioritize program investments

Requirements

What you’ll need

8+ years of progressive experience in digital strategy, enterprise technology, or AI program leadership; prior experience at a life sciences, biotech, or regulated healthcare organization strongly preferred
Demonstrated ability to develop and execute AI or digital strategy in a matrixed, cross-functional environment
Track record of building or operating AI governance, risk classification, or responsible AI frameworks
Proven cross-functional leadership: ability to earn trust and drive outcomes across Cybersecurity, Legal, Clinical, and business functions without formal authority
Hands-on familiarity with enterprise AI platforms, LLM-based tools, and agentic frameworks, including policy administration and access controls
Strong executive communication and presentation skills; ability to advise senior leadership with clarity and appropriate precision
Demonstrated change management capability across organizations with varied adoption readiness
Direct experience in a clinical-stage or late-phase biotech or pharma environment, with working knowledge of GxP, 21 CFR Part 11, Annex 11, or comparable frameworks
Familiarity with agentic AI architectures and multi-tool orchestration in enterprise environments
Consulting background (Big 4 or strategy firm) with experience managing multi-stakeholder programs and external delivery partners
Working knowledge of FDA AI/ML guidance, EU AI Act, or NIST AI RMF as they apply to enterprise or clinical AI deployment

Benefits

Comp & perks

A great culture, grounded in our C.O.R.E. values: Caring, Original, Resilient and Egoless
Opportunity to work in a fast-paced, highly dynamic environment where you help shape the culture and company, wear multiple hats, and learn quickly
Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits
We provide competitive time off, including three weeks PTO, two one-week company-wide shutdowns a year and dedicated paid sick leave
Commitment to growing you professionally and providing access to resources to further your development
Apogee offers regular all team, in-person meetings to build relationships and problem solve

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

AI program leadershipdigital strategyAI governancerisk classificationenterprise AI platformsLLM-based toolsagentic frameworkschange managementGxPFDA AI/ML guidance

Soft Skills

cross-functional leadershipexecutive communicationpresentation skillstrust buildingoutcome drivingadvising senior leadershipcollaborationfacilitationengagementadaptability