Senior Medical Director, EoE

Apogee Therapeutics

Sr. Medical Director leading EoE clinical trials for Apogee Therapeutics in a fast-paced environment, focusing on strategic execution and collaboration.

Posted 5/18/2026full-timeRemote • 🇺🇸 United StatesSenior💰 $350,000 - $375,000 per yearWebsite

About the role

Key responsibilities & impact

Participate in the design and execution of clinical studies in a new therapeutic area (Gastroenterology)
Contribute clinical and strategic perspective to EoE development program through BLA
Serve as a medical monitor, working closely with the CRO, clinical operations, and pharmacovigilance on study execution, including but not limited to safety reporting, point of escalation for medical monitoring matters, development and execution of the Medical Monitoring Plan
Contribute to the design of trials, and develop protocols and other relevant documents for individual studies
Lead study start-up activities
Direct day-to-day clinical and medical execution of studies
Work closely with cross-functional colleagues, including, but not limited to, clinical operations, regulatory, biostatistics, and data management, to ensure timely and flawless execution of clinical plan
Partner with clinical operations on site selection, recruitment, and CRO management
Partner with medical affairs to build and maintain strong relationships with PIs, including support of Advisory and Scientific Boards and Investigator Meetings
Serve as primary medical point of contact for sites and PIs for the assigned study, as applicable

Requirements

What you’ll need

Education – MD is required
Board certification in Gastroenterology a plus (not required)
4 + industry experience as a medical monitor and/or medical director
Experience working on phase 2 and 3 clinical studies in Gastroenterology or related immunological conditions
Highly motivated team player with a growth mindset, can-do attitude and willing to learn from others
Effective communication skills with an ability to present to a variety of stakeholders and tailor message accordingly
Successfully exhibit Apogee’s C.O.R.E. values: Caring, Original, Resilient and Egoless
Position requires up to 25% travel including mandatory in-person attendance at All Hands meetings typically held twice per year and functional meetings, study-related activities, and medical conferences.

Benefits

Comp & perks

A great culture, grounded in our C.O.R.E. values: Caring, Original, Resilient and Egoless
Opportunity to work in a fast-paced, highly dynamic environment where you help shape the culture and company, wear multiple hats, and learn quickly
Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits
We provide competitive time off, including three weeks PTO, two one-week company-wide shutdowns a year and dedicated paid sick leave
Commitment to growing you professionally and providing access to resources to further your development
Apogee offers regular all team, in-person meetings to build relationships and problem solve

ATS Keywords

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Applicant Tracking System Keywords

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Hard Skills & Tools

clinical study designmedical monitoringprotocol developmentsafety reportingBLAphase 2 clinical studiesphase 3 clinical studiesGastroenterologyimmunological conditionsCRO management

Soft Skills

team playergrowth mindsetcan-do attitudeeffective communicationrelationship buildingpresentation skillsadaptabilitycollaborationleadershipproblem-solving

Certifications

MDBoard certification in Gastroenterology