Absci

AI Scientist, Drug Creation

Absci

full-time

Posted on:

Location: 🇺🇸 United States

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Salary

💰 $160,000 - $260,000 per year

Job Level

Mid-LevelSenior

Tech Stack

PythonPyTorch

About the role

  • Absci is a data-first AI drug creation company designing differentiated therapeutics using generative AI.
  • Develop AI models that generate and evaluate antibody therapeutic candidates for de novo antibody design.
  • Collaborate with cross-functional teams (disease biologists, structural biologists, wet lab scientists) to define design criteria and deliver AI designs.
  • Deploy deep learning models for structure-based and sequence-based antibody design, co-folding, binding prediction, and physics-based evaluation.
  • Collaborate with wet lab to design AI antibody libraries and wet lab workflows for in vitro assessment.
  • Analyze in silico and in vitro validation results and iteratively improve methodologies.
  • Communicate and present results to diverse audiences and publish high-impact research.

Requirements

  • PhD or equivalent experience in Machine Learning, Computer Science, Computational Biology, Computational Chemistry, Biophysics, or a related field
  • 3+ years of research experience at the intersection of machine learning and protein design, molecular modeling, or a related field, ideally including industry experience
  • Demonstrated experience in developing and applying molecular simulation and/or computational biophysics tools
  • Fluency in Python and familiarity with PyTorch
  • Comfortable with design, implementation, and evaluation of state-of-the-art AI algorithms for protein design and protein structure prediction
  • Expertise in large-scale model deployment
  • Demonstrated ability to work collaboratively in an ambitious, fast-paced, interdisciplinary environment, including with Wet Lab scientists.
  • Demonstrated excellence in cross-disciplinary communication and collaboration, and in presenting complex technical work to diverse audiences
  • Strong publication record in respected, high-impact journals and conferences
  • Basic understanding of the drug discovery process with an earnest desire to learn more
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