Translator

• serve as expert PK/PD modeler in cross-functional teams, to make model-informed decisions about drug discovery, modality selection, and dose prediction across therapeutic areas
• integrate in vitro and in vivo data to build PBPK, quantitative systems pharmacology (QSP), or other mechanistic modeling platforms of drug disposition and pharmacology, to support forward / reverse translation for both established and novel therapeutic targets
• guide software developers in the design of automated workflows for implementing modeling platforms, to inform human PK/PD and dose projections
• collaborate across the PDMB organization to develop modeling and simulation strategies to identify and optimize drug candidates
• provide scientific guidance and cross-functional supervision to a team of growing scientists
• mentor / supervise junior colleagues to perform the above duties and to grow the above capabilities.

Director, Translational PK/PD, PBPK Modeling

• Leading portfolio management activities for early-stage R&D programs (discovery through IND/Ph1) including owning the integrated view of the TA portfolio (timing, key milestones, risks, and dependencies), in partnership with the TA Lead and Discovery Core Team Leads
• Translating portfolio strategy into actionable plans, including synthesizing, and articulating portfolio strategy and translating it into execution
• Preparing regular reports and presentations for senior management/governance committees/leadership committees, with a focus on developing clear, data-driven insights and narratives to enable decision-making.
• Capturing and communicating various metrics on the portfolio, including resources, project distribution across sites, phases of development, etc. and translating these into actionable portfolio insights
• Providing our Company's organizational and process expertise to teams to enable navigation of discovery, development, and corporate governance and business requirements.
• Collaborating effectively with functional areas, support functions, and alliance partner functions (if applicable) to facilitate project/portfolio delivery.
• Managing or administrating strategic, cross-functional or cross-divisional management, governance, or alliance committees
• Proactively surfacing key risks, trade-offs, and opportunities across the portfolio, and driving alignment across stakeholders in support of decision-making
• Providing mentoring, coaching, and oversight to Specialist/Senior Specialist project/Portfolio Managers working on common projects
• Actively participating and completing ongoing training and personal development activities to increase leadership competency and to gain knowledge and skill in the discipline of project management and the business and science of pharmaceutical product discovery and development.
• Partnering with Finance to ensure resource/budget planning and management.
• Collaborating with IT and PMO colleagues to maintain portfolio tools, dashboards, and reporting systems.
• Identifying and implementing best practices in portfolio management and governance, to drive process improvements and operational efficiencies, including contributing to the continuous evolution of portfolio and governance processes within GPAM.

Associate Director, Discovery & Translational Portfolio Management

• Hanna Interpreting Services LLC connects bilingual and multilingual individuals with opportunities to serve as freelance interpreters.
• As an interpreter, you contribute to society by supporting language access for everyone.
• Set your availability and accept appointments on your schedule.
• Appointments are available Monday - Friday, 8 am - 5 pm.
• Interpreters start at $25 - $30 per hour, depending on availability, experience, and demand of the language.

K'iche' Interpreter

• Connect bilingual and multilingual individuals with potential opportunities to serve as a freelance interpreter or translator.
• Make a positive contribution to society in support of language access for everyone.
• Act as your own boss, set your availability, and accept appointments based on your schedule.
• Work on appointments available Monday - Friday, 8 am - 5 pm, though not guaranteed and based on need.
• Start work as independent contractors under a 1099 role, flexible to work in different settings as needed.

Q'eqchi' Interpreter

• Characterize and integrate biomedical data modalities — digital pathology (whole slide images), neuroimaging (PET, structural and functional MRI), omics (genomics, transcriptomics, proteomics, metabolomics), and longitudinal clinical data to develop specialized, domain-specific models for neurodegeneration.
• Build and refine data engineering pipelines that harmonize heterogeneous modalities — reconciling differences in spatial resolution, temporal scale, and dimensionality — into unified analytical frameworks.
• Identify where cross-modal integration produces genuine insight versus where it introduces noise or artifact, establishing ground truth for downstream AI evaluation.
• Critically assess AI-driven literature synthesis and automated “third reviewer” capabilities for detecting methodological weaknesses, logical gaps, and unsupported claims across data modalities.
• Establish standards for how agentic systems incorporate overlooked or contradictory evidence such as negative findings, failed clinical trials, etc. and evaluate whether these integrations generate genuinely novel hypotheses.
• Design evaluation frameworks for agentic AI systems operating across neuroscience data modalities — assessing whether models can reason credibly across imaging, omics, and clinical evidence.
• Develop benchmarks using synthetic and real-world multi-modal datasets that probe AI co-scientist capabilities under realistic research conditions, testing for robustness, reproducibility, and alignment with expert-level biomedical reasoning.
• Serve as a neurodegeneration domain expert within the AI/ML team, ensuring that model outputs remain anchored to clinically relevant disease questions.
• Translate evaluation findings into actionable guidance for AI system development, bridging computational and experimental perspectives.
• Publish evaluation methodologies and findings in leading journals and conferences (e.g., AD/PD, AAIC, NeurIPS).

Translational Postdoctoral Researcher – Agentic AI for Neurodegeneration

• serve as expert PK/PD modeler in cross-functional teams, to make model-informed decisions about drug discovery, modality selection, and dose prediction across therapeutic areas
• integrate in vitro and in vivo data to build PBPK, quantitative systems pharmacology (QSP), or other mechanistic modeling platforms of drug disposition and pharmacology, to support forward / reverse translation for both established and novel therapeutic targets
• guide software developers in the design of automated workflows for implementing modeling platforms, to inform human PK/PD and dose projections
• collaborate across the PDMB organization to develop modeling and simulation strategies to identify and optimize drug candidates
• provide scientific guidance and cross-functional supervision to a team of growing scientists
• mentor / supervise junior colleagues to perform the above duties and to grow the above capabilities

• Provide timely, high-quality pathology expertise to GSK leaders, scientists, and study teams, operating within GSK policies and regulatory frameworks.
• Guide and refine clinical development strategies across oncology (primary focus), respiratory, immunology, and infectious diseases, ensuring integration of histopathology, translational research, and precision medicine.
• Partner with biomarker scientists and translational research teams to enable rigorous biomarker strategies, including study selection, patient stratification, and hypothesis-driven assay deployment.
• Provide strategic and scientific oversight of clinical biomarker assay development and validation, both internally and through external laboratories and CROs.

Senior Director, Medical, Translational and Computational Pathologist

• Partner with the Clinical Teams, R&D Technologies and the RIIRU Early Pipeline Unit with focus on Respiratory portfolio to identify, establish biomarkers for decision making throughout clinical development phases
• Provide strategic leadership contributing to deep understanding of disease areas enabling the development and execution of translational research disease strategies
• Evaluate novel techniques and technologies (i.e. spatial transcriptomics) to inform translational initiatives, biomarker development and validation working in collaboration with platform teams
• Collaborate closely with cross-functional teams including the Translational Disease Teams, biology groups, biomarker platforms, Medicine Development Teams, HBSM, data-sciences, regulatory affairs, business development and commercial
• Establish and maintain strategic collaborations with academic institutions, contract research organizations (CROs), and other external partners
• Provide mentorship, guidance, and professional development opportunities to ensure a high-performing and motivated team.

See all jobs on JobTailor

Director, Translational PK/PD, PBPK Modeling

Associate Director, Discovery & Translational Portfolio Management

K'iche' Interpreter

Q'eqchi' Interpreter

Translational Postdoctoral Researcher – Agentic AI for Neurodegeneration

Director, Translational PK/PD, PBPK Modeling

Senior Director, Medical, Translational and Computational Pathologist

Director, Translational Science Lead – Respiratory