Translator

• Understands, synthesizes, and aligns biomarker and translational needs across Discovery and Development portfolios, including anticipated timing, in partnership with the Translational biomarker leads and cross-functional stakeholders
• Works with Translational, Biomarker, and cross-functional partners within a matrixed environment to ensure strategy is supported by executable plans, appropriate timelines, and realistic assumptions
• Maintains accurate portfolio data in enterprise databases
• Summarizes portfolio metrics, issues and documents/presentations for senior management/governance committees to inform decision-making, with a focus on strategy and execution of Translational work
• Provides our company's organizational and process expertise to teams to enable navigation of discovery, development, and corporate governance and business requirements
• Collaborates effectively with functional areas, support functions, and alliance partner functions (if applicable) to facilitate project/portfolio delivery
• Manages strategic, cross-functional or cross-divisional management, governance, or alliance committees
• Prepares for, facilitates, and documents outcomes of leadership team meetings, ensuring meetings have clear purpose and objectives and that conflict is surfaced and resolved
• Proactively identifies and helps address opportunities for process improvement in translational biomarker workflows, tools, and systems
• Provides mentoring, coaching, and oversight to Specialist/Senior Specialist project/Portfolio Managers working on common projects
• Actively participates and completes ongoing training and personal development activities to increase leadership competency and to gain knowledge and skill in the discipline of project/portfolio management and the business and science of pharmaceutical product discovery and development and associated translational activities
• Partners with Finance to ensure resource/budget planning and management

Associate Director, Discovery and Translational Portfolio Management

• The Grant Coordinator A/B works under the direction of our senior grants staff in a friendly, collaborative atmosphere.
• Helps to administer a portfolio which includes NIH, industry, and foundation funding.
• Portfolio consists of federal awards such as R01s, Fs and Ks, and a T32, and also clinical trials.
• Duties involve budget development, proposal submissions, award setup, subcontract setup and monitoring, maintaining financial and regulatory compliance for each project, financial transaction processing, monthly expense reporting, projections, and closeouts.
• S/he will also be responsible for payroll management, entering costing allocations, and processing payroll reallocations.
• Other duties will be performed as needed to support research administration within the Division of Translational Medicine & Human Genetics within the Department of Medicine.
• Grant Coordinator B will work mostly independently and will be immediately assigned an investigator portfolio.
• Coordinator B will assist senior personnel with complex projects as needed and to learn about these proposals and accounts.
• Coordinator B will advise investigators regarding budgeting and sponsor requirements.

Grant Coordinator, Department of Translational Medicine and Human Genetics

• Serve as a strategic bridge between business stakeholders and technical teams within the AI Accelerator
• Lead translation of business challenges into actionable AI use cases
• Partner with pod leads to understand business strategic objectives
• Elicit and structure requirements from product leads to convert them into actionable inputs
• Collaborate with product owners to support roadmap across product management team and engineering teams
• Define and track performance metrics post-deployment with product and data teams
• Prepare business teams for product demos and rollouts
• Foster a culture of clarity, transparency, and collaboration across teams

Director, Business Translator, Commercial

• Act as the translational medicine lead for assigned early Oncology programs (preclinical to Phase 1)
• Define and own biomarker and translational strategies, plans and decision-enabling datasets
• Identify cutting edge science and technological advances and incorporate them into biomarker strategies
• Develop program-specific translational plans including hypothesis-driven biomarker selection, assay strategy (fit-for-purpose), sample collection/handling, and statistical/analysis plans
• Provide critical scientific input into target validation and discovery phases, pharmacology, PK/PD, target engagement, mechanism-of-action and patient selection strategies across modalities
• Lead assay selection, qualification/validation strategy and oversight (internal and external CROs/diagnostic partners)
• Integrate preclinical model data with clinical development plans
• Serve as the primary cross-functional interface for translational questions

Director, Senior Director – Oncology Early Translational Biomarkers (Haematological Cancer)

• serve as expert PK/PD modeler in cross-functional teams, to make model-informed decisions about drug discovery, modality selection, and dose prediction across therapeutic areas
• integrate in vitro and in vivo data to build PBPK, quantitative systems pharmacology (QSP), or other mechanistic modeling platforms of drug disposition and pharmacology, to support forward / reverse translation for both established and novel therapeutic targets
• guide software developers in the design of automated workflows for implementing modeling platforms, to inform human PK/PD and dose projections
• collaborate across the PDMB organization to develop modeling and simulation strategies to identify and optimize drug candidates
• provide scientific guidance and cross-functional supervision to a team of growing scientists
• mentor / supervise junior colleagues to perform the above duties and to grow the above capabilities.

Director, Translational PK/PD, PBPK Modeling

• Leading portfolio management activities for early-stage R&D programs (discovery through IND/Ph1) including owning the integrated view of the TA portfolio (timing, key milestones, risks, and dependencies), in partnership with the TA Lead and Discovery Core Team Leads
• Translating portfolio strategy into actionable plans, including synthesizing, and articulating portfolio strategy and translating it into execution
• Preparing regular reports and presentations for senior management/governance committees/leadership committees, with a focus on developing clear, data-driven insights and narratives to enable decision-making.
• Capturing and communicating various metrics on the portfolio, including resources, project distribution across sites, phases of development, etc. and translating these into actionable portfolio insights
• Providing our Company's organizational and process expertise to teams to enable navigation of discovery, development, and corporate governance and business requirements.
• Collaborating effectively with functional areas, support functions, and alliance partner functions (if applicable) to facilitate project/portfolio delivery.
• Managing or administrating strategic, cross-functional or cross-divisional management, governance, or alliance committees
• Proactively surfacing key risks, trade-offs, and opportunities across the portfolio, and driving alignment across stakeholders in support of decision-making
• Providing mentoring, coaching, and oversight to Specialist/Senior Specialist project/Portfolio Managers working on common projects
• Actively participating and completing ongoing training and personal development activities to increase leadership competency and to gain knowledge and skill in the discipline of project management and the business and science of pharmaceutical product discovery and development.
• Partnering with Finance to ensure resource/budget planning and management.
• Collaborating with IT and PMO colleagues to maintain portfolio tools, dashboards, and reporting systems.
• Identifying and implementing best practices in portfolio management and governance, to drive process improvements and operational efficiencies, including contributing to the continuous evolution of portfolio and governance processes within GPAM.

Translator jobs in Pennsylvania

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Associate Director, Discovery and Translational Portfolio Management

Grant Coordinator, Department of Translational Medicine and Human Genetics

Director, Business Translator, Commercial

Director, Senior Director – Oncology Early Translational Biomarkers (Haematological Cancer)

Director, Translational PK/PD, PBPK Modeling

Associate Director, Discovery & Translational Portfolio Management