Clinical Research

• Provide statistical input into clinical development plans, concept sheets, and study protocols.
• Perform statistical analyses and interpret clinical trial data to support decision making.
• Contribute to the preparation of statistical analysis plans (SAPs) and clinical study reports.
• Develop and implement statistical and machine learning models to support analysis of clinical study data.
• Write code to build and apply analytical models within study analyses, including predictive or exploratory modelling approaches where appropriate.
• Apply statistical techniques, machine learning, or Bayesian methods to uncover insights in clinical datasets.
• Design and perform hypothesis testing and exploratory analyses to support clinical development questions.
• Conduct statistical analyses using R and/or Python, with SAS used where required.
• Work primarily within the biostatistics team to deliver high-quality analyses for clinical studies.
• Clearly communicate analytical results and statistical concepts to stakeholders within the study team.

Principal RWD Biostatistician

• Managing the day-to-day operational delivery of the study, including timelines, milestone tracking, and documentation.
• Developing and maintaining study materials – e.g. protocol documentation, participant information sheets, and consent forms.
• Coordinating patient recruitment and randomisation in line with the study protocol.
• Owning participant communications from invitation through to study closure, ensuring a high-quality patient experience.
• Coordinating quantitative and qualitative data collection across both study arms, in collaboration with the data science team.
• Maintaining accurate study documentation – e.g. participant records, protocol deviations, and operational logs.
• Supporting the preparation of monthly performance reports, interim analysis, and the final study report.
• Liaising across internal teams (data, coaching operations, clinical teams, platform) and with the external Lilly project team as required.
• Collaborating with the Senior Behavioural Medicine team to design, develop, and iteratively refine the 6-week autonomy-supportive group coaching series.
• Applying evidence-based behaviour change frameworks (COM-B, Self-Determination Theory, Motivational Interviewing, BCTs) to session structure and content.
• Developing the full suite of session materials: facilitator guides, participant workbooks, activity prompts, and follow-up email content.
• Designing the MBQ phenotype-feedback process for participants, ensuring the autonomy and personalisation lever is activated effectively from Week 1.
• Supporting the piloting and refinement of the intervention ahead of launch, incorporating participant and coach feedback.
• Developing and maintaining intervention fidelity documentation and coaching quality standards for the delivery team, working with key stakeholders to ensure safe delivery, appropriate escalation pathways, and clinical oversight of coaching content.
• Delivering the 6-week group coaching series to intervention arm participants via live virtual sessions.
• Applying the MBQ-informed, autonomy-supportive coaching approach, tailoring facilitation to the phenotype profiles and individual needs within each cohort.
• Using evidence-based techniques including motivational interviewing, values clarification, goal-setting, self-efficacy building, and environmental design.
• Maintaining accurate session records and contributing observational data to the qualitative outcome stream.
• Supporting participant retention and engagement throughout the programme, proactively identifying and addressing disengagement risk.
• Escalating any clinical or safeguarding concerns in line with Numan's protocols.

Intervention & Research Coordinator – Clinical Research

• Supervise, advise and review: Leverage your expertise.
• Develop complex analysis strategies and execute them using efficient programming techniques (software: SAS, R).
• Foster teamwork.
• Perform intricate statistical analyses and provide input to statistical reports.
• Share knowledge.
• Provide input to analysis plans, statistical reports, statistical sections of integrated clinical reports.
• Be a proactive advisor for all types of analysis from the proposal process through the project life cycle.
• Review analysis data sets and quality control all types of statistical analysis deliverables.
• Coach and mentor. Train and uplift junior members of the department.
• Liaise with other biostatistical and company departments to optimize global efficiency.

Senior Biostatistician

• Lead the delivery of clinical and real-world evidence research projects from set-up through to completion.
• Develop research protocols, study documentation, ethics applications, governance submissions, SOPs, and operational processes.
• Manage and mentor research staff, supporting their development while maintaining high standards of scientific and operational excellence.
• Oversee participant recruitment, follow-up, data collection, quality assurance, and study compliance.
• Monitor study progress, identify risks, and implement solutions to ensure successful project delivery.
• Ensure all research activities comply with Good Clinical Practice (GCP), GDPR, research governance, and regulatory requirements.
• Analyse and interpret research data to support evidence generation and improve patient outcomes.
• Prepare research reports, publications, presentations, and evidence summaries.
• Work collaboratively with multidisciplinary teams, academic partners, and external stakeholders to integrate research into clinical care.
• Build strong relationships across internal and external teams to support successful research delivery.

Clinical Research Scientist

• Sets up and maintains excellent R-based computing environment.
• Adds missing features to apps and fixes bugs in existing apps.
• Screens the market for supplied data visualization tools and integrates internal/external apps into our working environment.
• Organizes and performs user trainings and is available for user support on demand.
• Is up to date with the latest technical possibilities available on the global market.
• Serves as a statistical department resource, mentors biostatisticians on job skills, and oversees or develops training plans or materials for Biostatistics associates.
• Conducts training sessions, or otherwise trains new hires and enhance the skills of existing personnel.
• Directs the activities of other biostatistics personnel on assigned projects to ensure timely completion of high quality work.
• Provides independent review of project work produced by other biostatisticians in the department.
• Provides support across all statistical tasks during the lifecycle of the project, from protocol to CSR.
• Prepares or oversees the preparation of Statistical Analysis Plans (SAPs), including development of well-presented mock-up displays for tables, listings, and figures.
• Collaborates with sponsor, if required.
• May be responsible as Lead Biostatistician for the statistical aspects of the protocol, generation of randomization schedule, and input to the clinical study report.
• Creates or reviews programming specifications for analysis datasets, tables, listings, and figures.
• Reviews SAS annotated case report forms (CRFs), database design, and other study documentation to ensure protocol criteria are met and all data is captured as required to support a high quality database and the planned analysis.
• Implements company objectives, and creates alternative solutions to address business and operational challenges.
• As biostatistics representative on project teams, interfaces with other departmental project team representatives preparing in advance for internal meetings, contributing ideas, and demonstrating respect for opinions of others.
• Conducts and participates in verification and quality control of project deliverables, ensuring that output meets the expected results and is consistent with analysis described in the SAP and specifications.
• May lead complex or multiple projects (e.g. submissions, integrated analyses), and attend regulatory agency meetings or responds to questions, as needed, to support the statistical analysis results of clinical trials on behalf of the sponsor.
• Manages scheduling and time constraints across multiple projects, sets goals based on priorities from management, discusses time estimates for completion of study related activities with biostatistics management, adapts to timeline or priority changes by reorganizing daily workload, and proactively communicates to biostatistics management any difficulties with meeting these timelines.
• Monitors progress on study activities against agreed upon milestones and ensures the study timelines for project deliverables are met.
• Identifies out of scope tasks and escalates to management.
• Provides statistical programming support as needed.
• May participate in Data Safety Monitoring Board (DSMB) and/or Data Monitoring Committee (DMC) activities, including charter development and serving as an independent non-voting biostatistician.
• May serve as a voting statistician on DSMBs and/or DMCs.
• Provides input and reviews, and subsequently follows applicable SOPs, WIs, and relevant regulatory guidelines (e.g. ICH).

Principal Biostatistician, Sr Biostatistician – R/Rshiny

• Exhibits strong study operational strategy to plan and oversee execution of assigned studies
• Acts as Study Team Leader and primary operational contact for 1–3 trials of average design and protocol complexity
• Responsible for the implementation, conduct and tracking of study trials in compliance with ICH/GCP and local regulations
• Provides operational and strategic leadership to assure successful delivery of trials
• Provides oversight of clinical sites, CROs and vendor activities
• Leads or participates in clinical site assessments
• Contributes to plans and study documents from an operational standpoint

Senior Clinical Study Manager

• Provide statistical support for CMC-related studies, including formulation development, stability studies, process validation, and analytical method validation.
• Collaborate with cross-functional teams, including analytical scientists, process engineers, and regulatory affairs, to develop and implement appropriate statistical strategies.
• Design and analyze experiments using linear mixed models, particularly for stability and variability analyses.
• Perform statistical modeling, data visualization, and simulations using R programming.
• Experience with Bayesian methods preferred.
• Ensure quality and compliance with internal standards and regulatory guidelines (e.g., FDA, EMA, ICH).

Principal Biostatistician – Chemistry, Manufacturing and Control

• Leadership and Project Management: Lead efforts in statistical operations to achieve quality and on time delivery
• Statistical Planning and Methodologies: Provide statistical expertise for clinical trials and research projects
• Statistical Programming: Develop and/or review ADaM dataset specifications
• Statistical Analysis and Reporting: Perform statistical analyses as per SAP and contribute to reporting meetings

• Deliver high-quality clinical research across the North West via EMS mobile research units.
• Conduct participant visits, supporting recruitment and ensuring clinical care and data integrity.
• Support a variety of studies, including obesity-focused and lifestyle interventions.
• Collaborate closely with the Senior Research Nurse and site teams to achieve study objectives.
• Maintain safe, organised, and efficient mobile unit operations.
• Provide participants with clear information and ensure informed consent.
• Escalate clinical or operational issues as appropriate.
• Attend team meetings, training sessions, and contribute to improvement initiatives.

Agile Clinical Research Nurse

• Prioritize multiple tasks, plan proactively, and accomplish goals using well-defined instructions.
• Participate in and manage project meetings and conference calls with CROs, vendors, and multi-functional teams.
• Able to anticipate obstacles and proactively develop solutions to achieve project goals.
• Develop a general understanding of functional issues and routine project goals from an organizational perspective.
• Participate in abstract presentations, oral presentations, and manuscript development activities.
• Interact and cooperate with individuals in other functional areas to address routine study issues.
• Develop tools and processes that increase measured efficiencies of the project.
• Assist in training for Clinical Trials Management Associates (CTMAs) and Clinical Project Assistants (CPAs).
• Assist in selecting Contract Research Organizations (CROs) or vendors.
• Coordinates CROs and vendors.
• Responsible in updating of study timelines.

Single Sponsor Clinical Trial Manager I, French speaking

• Serves as a statistical department resource
• Conducts training sessions for new hires
• Prepares Statistical Analysis Plans (SAPs)
• Reviews SAS annotated case report forms (CRFs)
• Directs activities of other biostatistics personnel
• Provides independent review of project work
• Supports business development activities
• Performs other work-related duties as assigned

Principal Biostatistician – Future Roles

• Support late-phase clinical development by contributing to protocol development, study start-up, data review and monitoring, and analysis activities
• Working collaboratively with the study team and clinical leadership to ensure high-quality, decision-ready clinical data
• Assist in authoring clinical protocols, Investigators Brochures, and other regulatory documents ensuring consistency and clarity
• Provide input into & implementation of data management plan, CRF design, and data review oversight
• Support review, analysis, and presentation preparation of clinical trial data for internal decision making, external interactions, and regulatory submission
• Assist Development Lead and Clinical Scientist Director in medical monitoring and management of collaborators, consultants, and/or Clinical Research Organizations in completion of key projects
• Anticipate and actively manage problems across a broad spectrum of cross-functional teams
• Work cross-functionally within teams to ensure clinical strategy is translated into the development of the study concept document, study protocol, and related documents
• Support appropriate training, recruitment, and development requirements for matrix team resources

Clinical Research jobs in United Kingdom

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Principal RWD Biostatistician

Intervention & Research Coordinator – Clinical Research

Senior Biostatistician

Clinical Research Scientist

Principal Biostatistician, Sr Biostatistician – R/Rshiny

Senior Clinical Study Manager

Principal Biostatistician – Chemistry, Manufacturing and Control

Senior Biostatistician

Agile Clinical Research Nurse

Single Sponsor Clinical Trial Manager I, French speaking

Principal Biostatistician – Future Roles

Clinical Scientist Associate Director, Late Development, Obesity